Results 41 to 50 of about 363,878 (298)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Verbal Valency- Decreasing Patterns in Persian [PDF]

open access: yesمطالعات زبان‌‌ها و گویش‌های غرب ایران, 2014
This article deals with different valency-changing patterns across languages. We refer to the configuration of arguments that a predicate needs to express a proposition as its valence pattern (or  argument structure(Grimshaw 1990).
Rezvan Motavalian
doaj  

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

open access: yesFEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos   +3 more
wiley   +1 more source

The left edge of the word in the Berber derivational morphology

open access: yesGlossa, 2018
In many Berber varieties, causative and reciprocal verbs are built by means of monoconsonantal prefixes attached to a stem. These prefixes are realized as single or geminated depending on the properties of the stem.
Mohamed Lahrouchi
doaj   +2 more sources

Reciprocal Alternations in Persian [PDF]

open access: yes̒Ilm-i Zabān, 2019
An alternation is defined as a pair of sentences with more or less identical structures and the same meaning. These alternations are sensitive to the meaning component of verbs.
Maryam Ghiasvand, Omid Tabibzadeh
doaj   +1 more source

Reciproc Blue: The New Generation of Reciprocation

open access: yesDental News, 2017
Aim: This article introduces the Reciproc1 blue system and describes the clinical technique with and without creating a glide path. Methodology: The concept of canal preparation with only one mechanical instrument used in reciprocation was introduced several years ago.
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Original form of Kepler's Third Law and its misapplication in Propositions XXXII-XXXVII in Newton's Principia (Book I)

open access: yesHeliyon, 2019
The original form of Kepler's Third Law contains a caveat regarding the requirement of small eccentricities – a fact that has not been incorporated by the traditional Newtonian derivations.
Gopi Krishna Vijaya
doaj  

The Principle of Reciprocity

open access: yesJournal of Magnetic Resonance, 2011
The circumstances surrounding the realisation that NMR signal reception could be quantified in a simple fundamental manner using Lorentz's Principle of Reciprocity are described. The poor signal-to-noise ratio of the first European superconducting magnet is identified as a major motivating factor, together with the author's need to understand phenomena
openaire   +4 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

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