Results 51 to 60 of about 235,823 (303)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

PLANT COVE R DIVERSITY OF TECHNOZEMES OF RECLAMATION LAND AT THE NIKOPOL MANGANESE ORE BASIN [PDF]

open access: yes, 2018
The study of the disturbed natural complexes evolution processes is important for the development of the most effective and rational methods of reclamation.
Andrusevych, Kateryna
core  

Some Observations on Optimal Frequency Selection in DVFS-based Energy Consumption Minimization

open access: yes, 2011
In recent years, the issue of energy consumption in parallel and distributed computing systems has attracted a great deal of attention. In response to this, many energy-aware scheduling algorithms have been developed primarily using the dynamic voltage ...
Rizvandi, Nikzad Babaii   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

National Water Resources Policy Issues [PDF]

open access: yes, 1957
Syftet med mitt arbete är att undersöka vad elever i klass 7 och klass 8 som läser spanska som andra språk ser som motiverande för sina spanskstudier. Jag ville även titta närmare vad som kan skapa motivation hos eleverna.
Fox, Irving K.
core   +3 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Influence of the Reclamation Process Intensity in the REGMAS Reclaimer on the Purification Degree of the High-silica Matrix

open access: yesArchives of Foundry Engineering, 2016
The investigation results of the reclamation of spent moulding sands with furfuryl resin are presented in this paper. The reclamation process was performed in the secondary reclamation chamber of the REGMAS 1.5 vibratory reclaimer.
Skrzyński M., Dańko R.
doaj   +1 more source

PROCEDURAL AND INSTITUTIONAL ASPECTS OF CREATING AND FUNCTIONING A COOPERATIVE RECLAMATION PARK

open access: yesНаучный журнал Российского НИИ проблем мелиорации, 2020
The purpose of this article was to disclose a step-by step procedure for creating an agricultural consumer cooperative with the functions of a reclamation park, which may include the participation of the Federal State Budgetary Institution “Land ...
L. A. Voyevodina, O. V. Voyevodin
doaj   +1 more source

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