The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Editorial: Innovative insights into pattern recognition and signaling in innate immunity. [PDF]
Granucci F, Kishore U.
europepmc +1 more source
Pattern Recognition for Typification of Whiskies and Brandies in the Volatile Components using Gas Chromatographic Data [PDF]
Sungmin Myoung, Chang-Hwan Oh
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Impact of mask-wearing on emotion recognition accuracy and fixation duration in young children. [PDF]
Lee J, Lee H, Kim M, Chung C.
europepmc +1 more source
Power Spectrum Analysis for Aerial Photo Recognition
Qizhen He Yongbao Liu, 何永保
openalex +2 more sources
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
TinyAct: A framework for real-time action recognition in the cloud through distillation learning. [PDF]
Wanna Y, Wiratchawa K, Intharah T.
europepmc +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Intelligent design and application of molecular recognition hydrogels in tissue engineering. [PDF]
Xue H +6 more
europepmc +1 more source

