Results 281 to 290 of about 1,760,183 (325)
Some of the next articles are maybe not open access.
Fold recognition from sequence comparisons
Proteins: Structure, Function, and Genetics, 2001We applied a new protocol based on PSI-Blast to predict the structures of fold recognition targets during CASP4. The protocol used a back-validation step to infer biologically significant connections between sequences with PSI-Blast E-values up to 10.
Koretke, K. +2 more
openaire +3 more sources
Signal sequence recognition and protein targeting
Current Opinion in Structural Biology, 1999Intracellular traffic is often controlled not by highways, but by handshakes and partner introductions within a cellular network. Recently determined structures suggest how signal sequences are recognized and how the GTP affinities of the signal recognition particle and its receptor are coupled to the targeting of ribosomes to translocational membrane ...
R M, Stroud, P, Walter
openaire +2 more sources
Rational recognition of nucleic acid sequences
Current Opinion in Biotechnology, 1999Recent progress in synthetic and computational chemistry has made it possible to develop certain novel drug candidates. Drug candidates for genetic diseases, such as cancer, may also be designed on the basis of structural information obtained using X-ray analysis and NMR, as well as evidence from biological techniques applied to natural products - DNA (
H, lida, G, Jia, J W, Lown
openaire +2 more sources
Hybrid object recognition in image sequences
Proceedings. Fourteenth International Conference on Pattern Recognition (Cat. No.98EX170), 2002We present a hybrid approach attaching probabilistic formalisms, as artificial neural networks or hidden Markov models, to concepts of a semantic network for a robust and efficient detection of objects. Additionally, an efficient processing strategy for image sequences is outlined which propagates the structural results of the semantic network as an ...
Kummert, Franz +3 more
openaire +2 more sources
Sequence-specific DNA recognition by polyamides
Current Opinion in Chemical Biology, 1999Sequence-specific DNA-binding small molecules that can permeate cells could potentially regulate transcription of specific genes. Simple pairing rules for the minor groove of the double helix have been developed that allow the design of ligands for predetermined DNA sequences. Some of these polyamides have been shown to inhibit specific gene expression
Dervan, Peter B., Bürli, Roland W.
openaire +3 more sources
Sequence-specific recognition of DNA nanostructures
Methods, 2014DNA is the most exploited biopolymer for the programmed self-assembly of objects and devices that exhibit nanoscale-sized features. One of the most useful properties of DNA nanostructures is their ability to be functionalized with additional non-nucleic acid components.
Rusling, David A., Fox, Keith R.
openaire +3 more sources
Recognition of Markovian sequences
2002A sequence being, perhaps, the simplest structure which for a number of reasons is best suited for us to use to start our talk on structural recognition. Even in such a simple special case it can be shown how to recognise a complex object which consists of many parts and how the knowledge of relations between the parts contributes to better recognition
Michail I. Schlesinger, Václav Hlaváč
openaire +1 more source
Recognition Sequence of a Restriction Enzyme
Nature New Biology, 1973Restriction endonuclease EcoRII makes about twenty double-stranded breaks per molecule of λh80 DNA. The 5′-terminal sequences are pC-C-A-G-G and pC-C-T-G-G. These are complementary and rotationally symmetrical, showing how the enzyme may produce DNA fragments with short cohesive ends.
C H, Bigger, K, Murray, N E, Murray
openaire +2 more sources
Spiking Neuron Model for Temporal Sequence Recognition
Neural Computation, 2010A biologically inspired neuronal network that stores and recognizes temporal sequences of symbols is described. Each symbol is represented by excitatory input to distinct groups of neurons (symbol pools). Unambiguous storage of multiple sequences with common subsequences is ensured by partitioning each symbol pool into subpools that respond only when ...
Byrnes, Sean +3 more
openaire +3 more sources
Sequence Recognition of DNA by Lexitropsins
Current Medicinal Chemistry, 2001Lexitropsins are modular polyamide molecules that are designed to "read" the base sequence of DNA. Lexitropsins constructed of three types of subunits--pyrrole, imidazole and hydroxypyrrole--allow full recognition of DNA base sequences. Structural studies have revealed the atomic basis of this specificity.
openaire +2 more sources