Results 201 to 210 of about 6,607,627 (360)

Recombinant Expression and Chemical Amidation of Isotopically Labeled Native Melittin. [PDF]

J Am Chem Soc, 2023
Gelenter MD, Bax A.
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Leaky recombinant expression reveals design constraints of bicistronic synthetic operons in Escherichia coli. [PDF]

Sci Rep
Gutmann S, Tauer C, Wagenknecht M, Striedner G, Grabherr R, Cserjan-Puschmann M.   +5 more
europepmc   +1 more source

Cloning, recombinant expression, purification, and functional characterization of AGAAN antibacterial peptide. [PDF]

3 Biotech, 2023
Ajingi YS, Rukying N, Jiddah NU, Koga Y, Jongruja N.   +4 more
europepmc   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

M9 medium composition alters E. coli metabolism during recombinant expression. [PDF]

J Biomol NMR
Dağ Ç, Gocenler O, Cakir N, Turğut M, Kazar AE.   +4 more
europepmc   +1 more source

Maquiberry Cystatins: Recombinant Expression, Characterization, and Use to Protect Tooth Dentin and Enamel. [PDF]

Biomedicines, 2023
de Souza EP, Ferro M, Pelá VT, Fernanda-Carlos T, Borges CGG, Taira EA, Ventura TMO, Arencibia AD, Buzalaf MAR, Henrique-Silva F.   +9 more
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Protocol for recombinant expression in E. coli and purification of iBoost vaccine proteins using immobilized metal affinity chromatography. [PDF]

STAR Protoc
Huijbers EJM, van Beijnum JR, Koetsier J, Wachholz GE, Kemper PCJ, Myburgh L, Meister S, van Loon K, Cassee MA, Griffioen AW.   +9 more
europepmc   +1 more source

Recombinant expression and antigenicity of two peptide families of neurotoxins from Androctonus sp. [PDF]

J Venom Anim Toxins Incl Trop Dis, 2022
Cardoso-Arenas S, Clement H, Arenas I, Olvera F, Zamudio F, Caliskan F, Corrales-García LL, Corzo G.   +7 more
europepmc   +1 more source