The Turkish Journal of Pediatrics, 2003 Transfusion of platelet concentrates remains the first-line therapy for Glanzmann thrombasthenia in case of bleeding or preparation for surgery. However, development of antibodies to platelet glycoprotein (Gp) IIb/IIIa complex or human leukocyte ...
Omer Devecioğlu +5 more
doaj
Acta Clinica Croatica, 2015 We present the use of recombinant activated factor VIIa (rFVIIa) in a 6-month-old infant that suffered massive bleeding and subsequent coagulation disturbances during elective surgery for choroid plexus carcinoma in the lateral ventricle.
Alenka Spindler Vesel +6 more
doaj
Case Reports in Neurology, 2012 We report on a 57-year-old woman with a pontine haemorrhage and an extremely prolonged activated partial thromboplastin time (aPTT) of more than 240 s, suggestive of a coagulation disorder.
Roger K. Schindhelm +5 more
doaj +1 more source
Assessing malpractice lawsuits for death or injuries due to amniotic fluid embolism [PDF]
, 2017 Amniotic fluid embolism (AFE) is a pregnancy complication known to be extremely hard to diagnose, since it manifests itself abruptly and with no warning signs, presenting an incidence rate of about 1 in 40000 deliveries, and maternal morbidity and ...
Marinelli, Enrico +2 more
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Emergency cesarean section in glanzmann thrombasthenia: Anaesthetic management without recombinant factor VIIa. [PDF]
Saudi J Anaesth, 2023 Priyanka A, Arulprakasam S, Rudingwa P.
europepmc +1 more source
PAR1 Agonists Stimulate APC-Like Endothelial Cytoprotection and Confer Resistance to Thromboinflammatory Injury [PDF]
, 2018 Stimulation of protease-activated receptor 1 (PAR1) on endothelium by activated protein C (APC) is protective in several animal models of disease, and APC has been used clinically in severe sepsis and wound healing.
Aisiku, Omozuanvbo +10 more
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A surveillance system to assess the need for updating systematic reviews. [PDF]
, 2013 BackgroundSystematic reviews (SRs) can become outdated as new evidence emerges over time. Organizations that produce SRs need a surveillance method to determine when reviews are likely to require updating.
Ahmadzai, Nadera +11 more
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Pregnant Women with Severe Factor VII Deficiency Undergoing Cesarean Section Managed with a Short-Term Regimen of Recombinant Factor VIIa. [PDF]
Matern Fetal Med, 2023 Obore N +5 more
europepmc +1 more source
Patient with congenital factor VII deficiency undergoing brain tumor neurosurgery successfully treated with recombinant factor VIIa and fresh frozen plasma: A case report and literature review. [PDF]
Medicine (Baltimore), 2023 Huang C, Yu Y, Zhai N, Mo W, Lin F.
europepmc +1 more source
Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]
, 2003 Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike +9 more
core +1 more source