Results 151 to 160 of about 7,837 (201)

Transformative approaches in hemophilia management: from traditional therapies to prenatal stem cell treatment. [PDF]

open access: yesFront Bioeng Biotechnol
Kao YT   +7 more
europepmc   +1 more source

Safety profile of recombinant factor VIIa

Seminars in Hematology, 2004
Recombinant factor VIIa (rFVIIa; NovoSeven(R), Novo Nordisk, Bagsvaerd, Denmark) has been used for many years in the successful management of bleeding episodes in patients with hemophilia and inhibitors. More recently, rFVIIa has also shown considerable success as a hemostatic agent in trauma and surgery patients without pre-existing coagulopathy ...
Dougald M Monroe, Maureane Hoffman
exaly   +3 more sources

Recombinant Factor VIIa

BioDrugs, 1999
Recombinant factor VIIa is a preparation of activated coagulation factor VII (factor VIIa) that is produced by recombinant DNA technology. The drug expedites blood coagulation without the need for factors VIII and IX in patients with haemophilia. Indicators of activation of systemic coagulation of blood were unchanged and mean prothrombin times and ...
C J, Dunn, C M, Spencer
openaire   +4 more sources

Recombinant factor VIIa

Emergency Medicine, 2004
Human coagulation factor (F) VII is a single chain protease that circulates in the blood as a weakly active zymogen at concentrations of approximately 10 nmol/L. When converted to the active 2 chain form (FVIIa), it is a powerful initiator of haemostasis. Recombinant factor VIIa (rFVIIa, eptacog alfa, NovoSeven) is a genetically engineered product that
openaire   +2 more sources

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