Results 21 to 30 of about 13,664 (205)

Recombinant activated factor VII in a patient with intracranial hemorrhage and severe thrombocytopenia

Clinical Case Reports, 2021
Hemorrhage in patients with hematologic malignancies is often difficult to manage as many of these patients also have coagulopathy and thrombocytopenia of varying severity.
Amir M. Ansari, Adam Khorasanchi, Armaghan Faghihimehr, Amir Toor   +3 more
doaj   +1 more source

Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves β1-integrin and extracellular signal regulated kinase activation [PDF]

, 2010
Objective: Increased levels of circulating tissue factor (TF) in the form of microparticles increase the risk of thrombosis. However, any direct influence of microparticle-associated TF on vascular endothelial cell proliferation is not known.
Collier, Mary E. W., Ettelaie, Camille
core   +2 more sources

Use of recombinant factor VIIa for hip surgery in a patient with factor-VII deficiency: A case report [PDF]

, 2007
patient with factor-VII deficiency: A case ...
Cashen, Amanda F., Clohisy, John C., Eby, Charles S., Gopalan, Priya K.   +3 more
core   +3 more sources

How we treat bleeding associated with direct oral anticoagulants [PDF]

, 2016
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +4 more
core   +1 more source

Control of disseminated intravascular coagulation in Klippel-Trenaunay-Weber syndrome using enoxaparin and recombinant activated factor VIIa: a case report

Journal of Medical Case Reports, 2010
Introduction Vascular malformation is associated with coagulopathies, especially when hemostasis is challenged. Case presentation We present the case of an 11-year-old Hispanic girl with Klippel-Trenaunay-Weber syndrome that developed disseminated ...
Kecskes Susan, Hast Howard, Schmidt Mary, Beier Ulf H, Valentino Leonard A   +4 more
doaj   +1 more source

Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hoc analysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial [PDF]

, 2007
BACKGROUND: Trauma is a leading cause of mortality and morbidity, with traumatic brain injury (TBI) and uncontrolled hemorrhage responsible for the majority of these deaths.
Yoram Kluger, Bruno Riou, Rolf Rossaint, Sandro B Rizoli, Kenneth Boffard, Philip Choong, Brian Warren, Michael Tillinger   +7 more
core   +1 more source

Activated recombinant factor VIIa should not be used in patients with refractory variceal bleeding: it is mostly ineffective, is expensive, and may rarely cause serious adverse events [PDF]

, 2014
Activated Recombinant Factor VIIa Does Not Improve Mortality in Variceal Bleeding. Bendtsen F, D’Amico G, Rusch E, de Franchis R, Anderson PK, Lebrec D, et al. Effect of recombinant Factor VIIa on outcome of acute variceal bleeding: An individual patient
Chalasani, Naga, Sozio, Margaret S.
core   +1 more source

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia [PDF]

, 2013
This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2012, Issue 3. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic
Ahonen, Ashrani, Bacigalupo, Bijsterveld, Bijsterveld, Boffard, Boffard, Boffard, Bosch, Bosch, Bysted, Chuansumrit, Davis, Diprose, Diringer, Ekert, Elgafy, Ensor, Essam, Fridberg, Friederich, Friederich, Friederich, Gill, Greisen, Gurusamy, Hanna, Hauser, Hauser, Hedner, Herbertson, Hsia, Isbister, Jeffers, Jilma, Johansson, Johansson, Key, Key, Kolban, Larsen, Leduc, Levi, Lin, Lin, Lipworth, Lodge, Lodge, Lodge, Lodge, Logan, Logan, Lusher, Ma, Macieji, Martí-Carvajal, Mayer, Mayer, Mayer, Mayer, Mayer, Mayer, Narayan, Nishijima, O'Connell, Perel, Perez, Pickard, Pickard, Pihusch, Plaat, Planinsic, Pugh, Pugliese, Ranucci, Raobaikady, Roberts, Sachs, Shao, Stanworth, Strydom, Thabut, Velde, Vincent, Vink, Woltz, Yank, Yank, You, Yuan   +89 more
core   +1 more source

Comparison of 3-Factor Prothrombin Complex Concentrate and Low-Dose Recombinant Factor VIIa for Warfarin Reversal. [PDF]

World J Emerg Surg, 2014
INTRODUCTION: Prothrombin complex concentrate (PCC) and recombinant Factor VIIa (rFVIIa) have been used for emergent reversal of warfarin anticoagulation. Few clinical studies have compared these agents in warfarin reversal. We compared warfarin reversal
Chapman SA, Irwin ED, Abou-Karam NM, Rupnow NM, Hutson KE, Vespa J, Roach RM.   +6 more
europepmc   +2 more sources

Dental Management of Glanzmann's Thrombasthenia in a 4-Year-Old Child With Rampant Caries: A Case Report and Literature Review. [PDF]

Clin Case Rep
ABSTRACT Glanzmann's Thrombasthenia (GT) is a rare congenital bleeding disorder in children, caused by the absence or dysfunction of glycoprotein (GP) IIb/IIIa, a receptor located on the platelet membrane. Proper oral health and regular dental appointments are crucial for these patients. However, maintaining good oral hygiene is challenging among them.
Nazemisalman B, Bahmani G, Davari K, Zarabadi MS.   +3 more
europepmc   +2 more sources