Results 21 to 30 of about 13,745 (204)

Low-dose recombinant factor VIIa for massive bleeding

Swiss Medical Weekly, 2011
QUESTIONS UNDER STUDY: recombinant activated factor VII (rFVIIa) is used off-label for massive bleeding. There is no convincing evidence of the benefits of this practice and the minimal effective dose is unknown.
A Mordasini, M Luginbühl, B Regli, HP Kohler, D Inderbitzin, B Lämmle, L Alberio   +6 more
doaj   +1 more source

Modification of biological parameters after treatment with recombinant factor VIIa in a patient with thrombocytopathy due to storage pool disease [PDF]

, 2005
Patients with thrombocytopathy due to storage pool disease mostly suffer from mild bleeding diathesis. However surgical interventions can lead to excess bleeding.
Almeida, Bick, Hoffman, Kristensen, Lisman, Lisman, Lisman, Peters, Poon, Van Tilburg, White   +10 more
core   +3 more sources

Combination of novoseven and feiba in hemophiliac patients with inhibitors

Open Medicine, 2018
The aim of this study is to investigate the effective therapeutic combination of recombinant VIIa(Novoseven) and factor eight inhibitor bypass activity(FEIBA) drugs for the bleedings of adult hemophiliac patients with inhibitors.19 bleeding episodes of 5
Malkan Umit Yavuz, Aksu Salih
doaj   +1 more source

Recombinant activated factor VII in a patient with intracranial hemorrhage and severe thrombocytopenia

Clinical Case Reports, 2021
Hemorrhage in patients with hematologic malignancies is often difficult to manage as many of these patients also have coagulopathy and thrombocytopenia of varying severity.
Amir M. Ansari, Adam Khorasanchi, Armaghan Faghihimehr, Amir Toor   +3 more
doaj   +1 more source

Factor VIIa administration in traumatic brain injury: an AAST-MITC propensity score analysis. [PDF]

, 2018
Background:Recombinant factor VIIa (rFVIIa) has been used off-label as an adjunct in the reversal of warfarin therapy and management of hemorrhage after trauma. Only a handful of these reports are rigorous studies, from which results regarding safety and
Coimbra, Raul, Jurkovich, Gregory J, Lombardo, Sarah, Millar, D, Nirula, Ram   +4 more
core   +2 more sources

Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hoc analysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial [PDF]

, 2007
BACKGROUND: Trauma is a leading cause of mortality and morbidity, with traumatic brain injury (TBI) and uncontrolled hemorrhage responsible for the majority of these deaths.
Brian Warren, Bruno Riou, Kenneth Boffard, Michael Tillinger, Philip Choong, Rolf Rossaint, Sandro B Rizoli, Yoram Kluger   +7 more
core   +1 more source

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia [PDF]

, 2013
This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2012, Issue 3. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic
Ahonen, Ashrani, Bacigalupo, Bijsterveld, Bijsterveld, Boffard, Boffard, Boffard, Bosch, Bosch, Bysted, Chuansumrit, Davis, Diprose, Diringer, Ekert, Elgafy, Ensor, Essam, Fridberg, Friederich, Friederich, Friederich, Gill, Greisen, Gurusamy, Hanna, Hauser, Hauser, Hedner, Herbertson, Hsia, Isbister, Jeffers, Jilma, Johansson, Johansson, Key, Key, Kolban, Larsen, Leduc, Levi, Lin, Lin, Lipworth, Lodge, Lodge, Lodge, Lodge, Logan, Logan, Lusher, Ma, Macieji, Martí-Carvajal, Mayer, Mayer, Mayer, Mayer, Mayer, Mayer, Narayan, Nishijima, O'Connell, Perel, Perez, Pickard, Pickard, Pihusch, Plaat, Planinsic, Pugh, Pugliese, Ranucci, Raobaikady, Roberts, Sachs, Shao, Stanworth, Strydom, Thabut, Velde, Vincent, Vink, Woltz, Yank, Yank, You, Yuan   +89 more
core   +1 more source

Control of disseminated intravascular coagulation in Klippel-Trenaunay-Weber syndrome using enoxaparin and recombinant activated factor VIIa: a case report

Journal of Medical Case Reports, 2010
Introduction Vascular malformation is associated with coagulopathies, especially when hemostasis is challenged. Case presentation We present the case of an 11-year-old Hispanic girl with Klippel-Trenaunay-Weber syndrome that developed disseminated ...
Kecskes Susan, Hast Howard, Schmidt Mary, Beier Ulf H, Valentino Leonard A   +4 more
doaj   +1 more source

Use of recombinant factor VIIa for hip surgery in a patient with factor-VII deficiency: A case report [PDF]

, 2007
patient with factor-VII deficiency: A case ...
Cashen, Amanda F., Clohisy, John C., Eby, Charles S., Gopalan, Priya K.   +3 more
core   +3 more sources

The history and evolution of the clinical effectiveness of haemophilia type a treatment: a systematic review. [PDF]

, 2012
First evidence of cases of haemophilia dates from ancient Egypt, but it was when Queen Victoria from England in the 19th century transmitted this illness to her descendants, when it became known as the "royal disease".
A Aleem, A Farrugia, A Miners, A Mocroft, AL Dunn, BA Konkle, BL Evatt, BM Feldman, CA Lee, CL Poel Van der, Claudia P. Casas, D Dimichele, D Dimichele, E Berntorp, E Berntorp, E Santagostino, Hector E. Castro, J Astermark, J Goudemand, J Oldenburg, J Stachnik, J Tusell, J Wight, Juan David Rueda, K Porter, L Valentino, L Valentino, LM Aledort, M Carcao, M Carcao, M Depka Von, M Franchini, M Lloyd, M Makris, María Fernanda Briceño, MD Carcao, MV Ragni, P Petrini, PM Mannucci, PM Mannucci, R Prabhu, S Royal, SA Larsson, SC Darby, SC Gouw, T Wong, TL Chorba, VS Blanchette, WK Hoots   +48 more
core   +2 more sources