Results 41 to 50 of about 6,404 (193)

Breaking the cycle: considerations for a life-course vaccination strategy against varicella-zoster virus

Expert Review of Vaccines
Introduction Varicella-zoster virus (VZV) is a highly contagious virus that manifests as varicella (chickenpox) as primary infection and reactivates as herpes zoster (HZ, shingles), with the potential for severe complications.
Giacomo Casabona, Paolo Bonanni, Giovanni Gabutti, Volker Vetter, Maurine Duchenne, Raunak Parikh   +5 more
doaj   +1 more source

Efficacy, effectiveness, and safety of herpes zoster vaccine in the immunocompetent and immunocompromised subjects: A systematic review and network meta-analysis

Frontiers in Immunology, 2022
ObjectiveTo investigate the efficacy, effectiveness and safety of recombinant zoster vaccine (RZV) and zoster vaccine live (ZVL) in immunocompetent and immunocompromised subjects.MethodsData sources: PubMed, EMBASE, Cochrane Library, and Web of Science ...
Yue Xia, Xue Zhang, Liuren Zhang, Chuanxi Fu   +3 more
doaj   +1 more source

Prolonged Neurological and Musculoskeletal Symptoms Following Shingrix Vaccination

Reports
Background and Clinical Significance: The recombinant zoster vaccine (Shingrix) helps prevent shingles and its complications in adults 50 and older. While minor side effects are common, severe adverse reactions are thought to be rare, and long-term side ...
Sabrina Hollar, Amna Khalid, Benjamin D. Brooks, Michael Wons   +3 more
doaj   +1 more source

Safety profile of the adjuvanted recombinant zoster vaccine : Pooled analysis of two large randomised phase 3 trials [PDF]

, 2019
Background: The ZOE-50 (NCT01165177) and ZOE-70 (NCT01165229) phase 3 clinical trials showed that the adjuvanted recombinant zoster vaccine (RZV) was ≥90% efficacious in preventing herpes zoster in adults.
López-Fauqued, M.,, Oostvogels, L.,, Sanmartin Berglund, Johan,, McNeil, S. A., Ahonen, A.,, Barba-Gomez, J. F.,, Barba-Gomez, J. F., McElhaney, J. E., Avelino-Silva, T. J.,, Sanmartin Berglund, Johan, El Idrissi, M.,, Oostvogels, L., McNeil, S. A.,, McElhaney, J. E.,, Delannois, F.,, Delannois, F., Campora, L.,, Lal, H.,, De Looze, F. J., Campora, L., Ahonen, A., Diez-Domingo, J.,, Heineman, T. C.,, Avelino-Silva, T. J., Diez-Domingo, J., El Idrissi, M., Lal, H., De Looze, F. J.,, Tavares-Da-Silva, F.,, Yeo, W., Tavares-Da-Silva, F., Heineman, T. C., López-Fauqued, M., Yeo, W.,   +33 more
core   +2 more sources

Current status of immunisation for herpes zoster

Human Vaccines & Immunotherapeutics
Herpes zoster (HZ) is increasingly common in the aging and is experienced by approximately one in three people in their lifetime. It is also relatively common in immune-compromised people.
Anthony Lawrence Cunningham, Kerrie Jane Sandgren, Janette Taylor   +2 more
doaj   +1 more source

Awareness and acceptability of herpes zoster vaccination in people living with HIV

Preventive Medicine Reports
Objective: The recombinant herpes zoster vaccine is recommended for aging populations to prevent herpes zoster. We aimed to assess awareness of herpes zoster and acceptance of the herpes zoster vaccine acceptance among people living with HIV (PLWH ...
Christian Motet, Agnès Libois, Charlotte Martin, Nicolas Dauby   +3 more
doaj   +1 more source

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, EarlyView.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source

Guideline for the Diagnosis and Management of Heritable IFNAR1 Deficiency in Oceania

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Autosomal recessive interferon alpha and beta receptor subunit 1 (IFNAR1) deficiency is a rare and heritable inborn error of immunity (IEI) predisposing individuals to severe and life‐threatening viral infections. It is more common in people of Western Polynesian ancestry, with estimates of around one in six thousand live births affected, due ...
Cecilia Verryt, Paul Gray, Peter McNaughton, Jane Peake, Melanie Wong, George Aho, Emma Best, Maia Brewerton, Flora Lutui, Litara Esera Tulifau, Rebecca Qin, Satupa‘itea Viali, Petine White, Andrew Wood, See‐Tarn Woon, Theresa Cole, Alberto Pinzon Charry, Kuang‐Chih Hsiao   +17 more
wiley   +1 more source

IFN-α armed gE elicits superior immunogenicity compared to unmodified antigens and flagellin armed gE in mice

Vaccine: X
Herpes zoster (HZ) induces significant pain and discomfort, which can seriously affect the quality of life of patients. At present, there is no specific treatment for HZ, and the mosteffective HZ control is vaccination. The main obstacle to developing an
Jiangang Zhang, Shaodan Peng, Fang Xu, Ying Qiao, Xiaoke Ye, Yu Guan, Xiaolong Zhao, Yueran Wang, Zhongqi Shao, Tao Zhu, Weixue Si   +10 more
doaj   +1 more source

Advances in understanding the mechanism of action of adult vaccines

The Journal of Clinical Investigation, 2023
The occurrence of herpes zoster (HZ) correlates with declining memory T cells that had responded to earlier infection with varicella-zoster virus (VZV).
Anthony L. Cunningham, Kerrie J. Sandgren, Naomi R. Truong   +2 more
doaj   +1 more source