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Trained Immunity Generated by the Recombinant Zoster Vaccine
Abstract Trained immunity may play a role in vaccine-induced protection against infections. We showed that the highly efficacious recombinant VZV-gE zoster vaccine (RZV) generated trained immunity in monocytes, natural killer (NK) cells, and dendritic cells (DCs) and that the less efficacious live zoster vaccine did ...
Adriana Weinberg +5 more
openaire +2 more sources
Supplementary Material. Quality of Life Impact of an Adjuvanted Recombinant Zoster Vaccine in Adults Aged 50 Years and Older [PDF]
Supplementary Material Quality of Life Impact of an Adjuvanted Recombinant Zoster Vaccine in Adults Aged 50 Years and ...
Curra, Desmond +6 more
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This study aimed to compare the risk signals of Guillain–Barré syndrome (GBS) associated with recombinant zoster vaccine (RZV) and zoster vaccine live (ZVL) to improve understanding of herpes zoster vaccine safety.
Yinpeng Xu +4 more
doaj +1 more source
INTRODUCTION. Varicella zoster virus remains a serious threat to public health and is a significant burden on the health system due to treatment costs. Vaccination coverage against varicella zoster (VZ) and herpes zoster (HZ) remains low for a number of
A. V. Zotova, O. A. Svitich
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The recombinant zoster vaccine (RZV), which uses the AS01 adjuvant system, confers more than 90 % efficacy in older adults against herpes zoster. While most older adults have been exposed to chickenpox, it remains unclear why a two-dose schedule is ...
Cheung, Yin Bun +10 more
core +1 more source
Varicella-zoster virus (VZV), the cause of shingles, remains a significant health issue worldwide, particularly among aging populations. The recombinant zoster vaccine (Shingrix, RZV) is the only approved vaccine in many countries and has demonstrated ...
Wenhui Xue +19 more
doaj +1 more source
Immune responses to zoster vaccines
There are two licensed herpes zoster vaccines. One is a live vaccine (ZVL) based on an attenuated varicella-zoster virus (VZV). The other is a recombinant vaccine (RZV) based on the VZV glycoprotein E (gE) combined with AS01B, a multicomponent adjuvant ...
Myron J Levin, Adriana Weinberg
doaj +1 more source
Update on post-licensure safety monitoring of recombinant zoster vaccine (RZV, Shingrix) [PDF]
Zoster-2-Shimabukuro-508 ...
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Plenary Abstracts Session & Oral Presentations
HemaSphere, Volume 10, Issue S1, June 2026.
wiley +1 more source

