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CRISPR/Cas9-induced breaks are insufficient to break linkage drag surrounding the ToMV locus of Solanum lycopersicum. [PDF]
Grubben J+4 more
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Genetic recombination in plants
Current Opinion in Plant Biology, 1998Meiotic recombination generates novel allelic arrays on chromosomes. Recent experiments have revealed an extraordinarily nonrandom distribution of recombination breakpoints along the lengths of plant chromosomes; for example, recombination breakpoints often resolve within genic sequences, and thereby generate novel alleles.
Basil J. Nikolau+2 more
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Genetic Recombination in Streptomyces
Nature, 1955THE Actinomycetes have properties intermediate between those of the fungi and those of the bacteria. As in practically all bacteria and in many fungi, a sexual cycle is not known to occur in the Actinomycetes. In some bacteria and Fungi Imperfecti1, however, there are parasexual processes2, that is, processes leading to genetic recombination otherwise ...
G. Sermonti, I Spada-Sermonti
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Genetic analysis of recombination in prokaryotes
Current Biology, 1992Bacteria provide a simple system for the genetic analysis of homologous recombination. More than twenty genes have been identified in Escherichia coli. The enzymatic activities associated with the products of many of these genes have been revealed by studies with model DNA substrates. It is now possible to pair homologous molecules in vitro and process
Gary J. Sharples, Robert G. Lloyd
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Models of Genetic Recombination
Annual Review of Microbiology, 1974It will be my intention to compare established and recently proposed models for . genetic recombination, with special attention to the separate component principles they contain and the function ofthese principles in the various models. As increasing attention has been paid to realistic details of DNA structure and enzymology, recombination models have
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Genetic Recombination in Bacteriophage
1965Publisher Summary This chapter discusses the genetic recombination in bacteriophage. Although many aspects of the biochemistry, genetics, and general physiology of the system are pertinent to the question of recombination in bacteriophages, the chapter considers only certain facets of the problem. Specifically, the idea of some kind of phosphodiester
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Genetic Recombination in Malaria Parasites
Nature, 1971THE complexity of the life cycle of malaria parasites and the lack of suitable strain characters which could be used as genetic markers have made genetic studies of these organisms difficult. We have now available, however, a number of strains of Plasmodium berghei isolated from wild rodents and mosquitoes in Africa, which can be differentiated from ...
Richard Carter+2 more
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Genetics of Meiosis and Recombination in Mice
2012Meiosis is one of the most critical developmental processes in sexually reproducing organisms. One round of DNA replication followed by two rounds of cell divisions results in generation of haploid gametes (sperm and eggs in mammals). Meiotic failure typically leads to infertility in mammals.
Ewelina Bolcun-Filas, John C. Schimenti
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Initiation of genetic recombination and recombination-dependent replication
Trends in Biochemical Sciences, 2000Recombination initiates at double-stranded DNA breaks and at single-stranded DNA gaps. These DNA strand discontinuities can arise from DNA-damaging agents and from normal DNA replication when the DNA polymerase encounters an imperfection in the DNA template or another protein.
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Recombinant proteins for genetic disease
Clinical Genetics, 1999The era of molecular biology has led to the development of powerful tools capable of generating therapeutics for genetic disorders. Although there is much current emphasis placed on the development of ‘gene therapy’ for human disease, developments in the production and availability of recombinant proteins are likely to have a more substantial impact on
Christopher S. Russell, Lorne A. Clarke
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