Results 251 to 260 of about 546,503 (279)

The Theory of Genetical Recombination

1950
Publisher Summary The aim of genetical research is to determine the topography of the genetical material in various organisms and to represent the mutable genes on each chromosome as occupying positions on a linear map. The order and spacing of the genes in the main has to be inferred from the amounts of recombination exhibited by sets of genes when ...
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Genetic recombination in avian retroviruses

Journal of Cellular Biochemistry, 1982
AbstractThe avian retroviruses—and probably other retroviruses as well—undergo a variety of recombinational events with relatively high efficiency. An understanding of the molecular basis of these events should provide insight into the important biological properties these agents exhibit when they become integrated into somatic or germ‐line host cells,
A M, Skalka, L, Boone, R, Junghans, D, Luk   +3 more
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Genetic Recombination in Malaria Parasites

Nature, 1971
THE complexity of the life cycle of malaria parasites and the lack of suitable strain characters which could be used as genetic markers have made genetic studies of these organisms difficult. We have now available, however, a number of strains of Plasmodium berghei isolated from wild rodents and mosquitoes in Africa, which can be differentiated from ...
D, Walliker, R, Carter, S, Morgan
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Genetics of Meiosis and Recombination in Mice

2012
Meiosis is one of the most critical developmental processes in sexually reproducing organisms. One round of DNA replication followed by two rounds of cell divisions results in generation of haploid gametes (sperm and eggs in mammals). Meiotic failure typically leads to infertility in mammals.
Ewelina, Bolcun-Filas, John C, Schimenti
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Genetic analysis of recombination in prokaryotes

Current Biology, 1992
Bacteria provide a simple system for the genetic analysis of homologous recombination. More than twenty genes have been identified in Escherichia coli. The enzymatic activities associated with the products of many of these genes have been revealed by studies with model DNA substrates. It is now possible to pair homologous molecules in vitro and process
R G, Lloyd, G J, Sharples
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Recombinant proteins for genetic disease

Clinical Genetics, 1999
The era of molecular biology has led to the development of powerful tools capable of generating therapeutics for genetic disorders. Although there is much current emphasis placed on the development of ‘gene therapy’ for human disease, developments in the production and availability of recombinant proteins are likely to have a more substantial impact on
C S, Russell, L A, Clarke
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Initiation of genetic recombination and recombination-dependent replication

Trends in Biochemical Sciences, 2000
Recombination initiates at double-stranded DNA breaks and at single-stranded DNA gaps. These DNA strand discontinuities can arise from DNA-damaging agents and from normal DNA replication when the DNA polymerase encounters an imperfection in the DNA template or another protein.
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Evidence of genetic recombination in Leishmania

Molecular and Biochemical Parasitology, 1991
In the genus Leishmania there has been no convincing demonstration of genetic exchange, and it has been proposed that reproduction is clonal. However, preliminary characterization of two strains of Leishmania isolated from wild animals in a zoonotic focus of cutaneous leishmaniasis in the Eastern Province of Saudi Arabia, has suggested that they may ...
J M, Kelly, J M, Law, C J, Chapman, G J, Van Eys, D A, Evans   +4 more
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Group representation of genetic recombinations

The Bulletin of Mathematical Biophysics, 1964
An algebraic representation of operations of genetic recombinations is illustrated. It is shown that the recombinations between chromosomes in the two-strand model can be represented by groups, in the sense of the theory of groups. Recombinations between chromosomes with inversions and a translocation are considered as well as cases without them. It is
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Genetic control of intrachromosomal recombination

BioEssays, 1995
AbstractIntrachromosomal recombination between direct repeats can occur either as gene conversion events, which maintain exactly the number of repeat units, or as deletions, which reduce the number of repeat units. Gene conversions are classical recombination events that utilize the standard chromosome recombination machinery.
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