Results 71 to 80 of about 66,899 (270)

Applying Machine Translation and Language Modelling Strategies for the Recommendation Task of Micro Learning Service

open access: yesEducational Technology & Society, 2022
A newly emerged micro learning service offers a flexible formal, informal, or non-formal online learning opportunity to worldwide users with different backgrounds in real-time.
Jiayin Lin   +3 more
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A Context Aware Recommender System for Mobile Phone Selection Using Combination of Elimination Method and Analytic Hierarchy Processing

open access: yesIranian Journal of Information Processing & Management, 2017
Recommender systems suggest proper items to customers based on their preferences and needs. Needed time to search is reduced and the quality of customer’s choice is increased using recommender systems.
Jalal Rezaeenour, Fatemeh Sadat Lesani
doaj  

On Explainable Fuzzy Recommenders and their Performance Evaluation

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2019
This paper presents a novel approach to the design of explainable recommender systems. It is based on the Wang–Mendel algorithm of fuzzy rule generation.
Rutkowski Tomasz   +2 more
doaj   +1 more source

Optimal Pricing with Recommender Systems [PDF]

open access: yes
We study optimal pricing in the presence of recommender systems. A recommender system affects the market in two ways: (i) it creates value by reducing product uncertainty for the customers and hence (ii) its recommendations can be offered as add-ons ...
Deran Ozmen, Dirk Bergemann
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Efficient Recommender Systems [PDF]

open access: yes
We study the efficient allocation of buyers in the presence of recommender systems. A recommender system affects the market in two ways: (i) it creates value by reducing product uncertainty for the customers and hence (ii) its recommendations can be ...
Deran Ozmen, Dirk Bergemann
core  

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