Results 61 to 70 of about 1,342,494 (318)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Special Inspector General for Iraq Reconstruction [PDF]
, 2013 This is the website for the Office of the Special Inspector General for Iraq Reconstruction. SIGIR provides oversight for Iraq reconstruction programs and operations.
Special Inspector General for Iraq Reconstruction (U.S.)
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
20 years of EU Membership: What Explains the Accession Bonus? [PDF]
Financial and Economic Review2024 marked the 20th anniversary of the EU accession of ten economies. Their experience was characterised by rapid growth in per capita incomes. Of the 23 percentage points of average convergence observed between the EU-10 and Germany between 2003 and ...
Maxim Chupilkin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Report of the State Capitol Reconstruction Commission to the Governor and the Oregon Legislative assembly [PDF]
, 1937 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Began with January, 1937First report covers the period Dec ...
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Improving capacity for stabilization and reconstruction operations / [PDF]
, 2009 U.S. experiences in Iraq and Afghanistan have demonstrated that improving U.S. capacity for stabilization and reconstruction operations is critical to national security. To help craft a way ahead, the authors provide an overview of the requirements posed
Peterson, Heather. +4 more
core +1 more source
The evolution of robotics: research and application progress of dental implant robotic systems
International Journal of Oral ScienceThe use of robots to augment human capabilities and assist in work has long been an aspiration. Robotics has been developing since the 1960s when the first industrial robot was introduced.
Chen Liu +5 more
doaj +1 more source