Results 131 to 140 of about 32,466 (303)

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

open access: yesAdvanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu   +11 more
wiley   +1 more source

IMMUNIZATION INFORMATION SYSTEMS PATIENT-LEVEL DE-DUPLICATION BEST PRACTICES. June 25, 2013

open access: yes
Last Reviewed Feb 2016Patient-level de-duplication (also called patient matching, patient de-duplication, or patient identity management) is the process of finding and removing redundant patient records from a database.

core  

Sharing and viewing segments of electronic patient records service (SVSEPRS) using multidimensional database model [PDF]

open access: yes, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The concentration on healthcare information technology has never been determined than it is today.
Jalal-Karim, Akram
core  

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

open access: yesAdvanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou   +12 more
wiley   +1 more source

Simplified Record-Keeping Project for the Yelm School District Elementary Schools

open access: yes, 1984
The relationships of student record-keeping, student learning objective tracking, and student progress reporting were studied. The management problems of these record-keeping processes, such as teacher time spent on paperwork, the overabundance of ...
Higgins, Jerry L.
core  

PENOMORAN GANDA BERKAS REKAM MEDIS DI RSUD PASAR MINGGU

open access: yes, 2021
Good medical record numbering is one of the keys to the success or goodness of medical record management of a health service, of course if supported by a good system.
Rahmat, Irda Sari
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

open access: yesAdvanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang   +15 more
wiley   +1 more source

ASM incorporates Imagetwin to address image duplication and preserve scientific accuracy

open access: yes
Image duplication in scientific articles—accidental or intentional—undermines trust in research, authors, institutions, and publishers. Duplications not only cast doubt on researchers’ scientific rigor, but they also raise concerns about potential ...
Alicea Hibbard   +4 more
core   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

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