Results 101 to 110 of about 378,041 (330)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Leveraging Fuzzy Match: Building an Automated Record Linkage Template in SAS Dataflux

International Journal of Population Data Science
Background  ICES has conducted Probabilistic Record Linkage (PRL) for heath and non-health data for over 15 years. The PRL process has made data linkable to many ICES data holdings.
Charlotte Ma, Gangamma Kalappa, Nan Wang, Mahmoud Azimaee, Winnie Shen   +4 more
doaj   +1 more source

Randomized Response and Balanced Bloom Filters for Privacy Preserving Record Linkage [PDF]

, 2017
In most European settings, record linkage across different institutions is based on encrypted personal identifiers – such as names, birthdays, or places of birth – to protect privacy.
Schnell, R.
core  

The Data-Adaptive Fellegi-Sunter Model for Probabilistic Record Linkage: Algorithm Development and Validation for Incorporating Missing Data and Field Selection [PDF]

, 2022
Xiaochun Li, Huiping Xu, Shaun J. Grannis   +2 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

How Are Linkage Results Using Privacy-Preserving Record Linkage Different?

International Journal of Population Data Science, 2020
Introduction Privacy-Preserving Record Linkage (PPRL) presents opportunities to improve privacy protection when performing record linkage on the most sensitive data.
Michael Jarrett, Brent Hills, Yinshan Zhao, Adrian Brown, Sean Randall, James Boyd, Anna Ferrante, Kimberlyn McGrail   +7 more
doaj  

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Algorithmic Accountability for Record Linkage

International Journal of Population Data Science
This session will examine record linkage approaches through the lens of principles for algorithmic accountability: responsibility, explainability, accuracy, auditability, and fairness.[1] It is easy to hypothesize cases where linkage algorithms could ...
Emily Wiegand, Aya Liu, Sabrina Sedovic
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source