Results 61 to 70 of about 375,414 (281)

Validating Distance-Based Record Linkage with Probabilistic Record Linkage [PDF]

open access: yes, 2002
This work compares two alternative methods for record linkage: distance based and probabilistic record linkage. It compares the performance of both approaches when data is categorical. To that end, a distance over ordinal and nominal scales is defined.
Josep Domingo-Ferrer, Vicenç Torra
openaire   +1 more source

Validation of de-identified record linkage to ascertain hospital admissions in a cohort study [PDF]

open access: yes, 2011
BACKGROUND: Cohort studies can provide valuable evidence of cause and effect relationships but are subject to loss of participants over time, limiting the validity of findings.
Alison Beauchamp   +9 more
core   +4 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Implementing privacy-preserving record linkage: welcome to the real world

open access: yesInternational Journal of Population Data Science, 2017
Objectives While record linkage has become a strategic research priority within Australia and internationally, legal and administrative issues prevent data linkage in some situations due to privacy concerns.
James Boyd   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Performance Evaluation and Accuracy Improvement in Individual Record Linking Problems Using Decision Tree Algorithm in Machine Learning [PDF]

open access: yesIranian Journal of Information Processing & Management
Record linkage is a vital process for consolidating data from different sources, particularly in Persian records where diverse data structures and formats present challenges. To tackle these complexities, an expert system with decision tree algorithms is
Vadood Keramati   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Comparing Record Linkage methods for real-world perinatal and neonatal data without unique identifiers

open access: yesInternational Journal of Population Data Science, 2019
Background Data on newborns is regularly linked for epidemiological research. However, hospital data often suffers from incomplete data. We report on a linkage of two population-covering administrative health databases containing neonatal and perinatal ...
Rainer Schnell, Christian Borgs
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy