Results 121 to 130 of about 19,742,605 (382)

ELMV: an Ensemble-Learning Approach for Analyzing Electrical Health Records with Significant Missing Values [PDF]

, 2020
Lucas J. Liu, Hongwei Zhang, Jianzhong Di, Jin Chen   +3 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

On Estimation of Reliability Functions using Record values from Proportional Hazard Rate Model

Austrian Journal of Statistics, 2019
Two measures of reliability functions, namely R(t)=P(X>t) and P=P ...
Ajit Chaturvedi, Ananya Malhotra
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Record values and the exponential distribution

Journal of Applied Probability, 1981
Let X1, X2, · ·· be i.i.d. and Yk = max{X1, X2, · ··, Xk}. Then Xj is a record value of the sequence if Yj > Yj-1). Denoting record value times by Ln, n = 1, 2, ···, we prove that the independence of XLj − XLi and XLi with Lj > characterizes the exponential distribution.
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Paratecoma peroba (Record) Kuhlm. [MAK Value Documentation in German language, 1996] [PDF]

, 2012
Deutsche Forschungsgemeinschaft. Ständige Senatskommission zur Prüfung Gesundheitsschädlicher Arbeitsstoffe, Greim, Helmut   +1 more
openalex   +1 more source

Do People Value Recorded Music? [PDF]

Cultural Sociology, 2019
How much do the majority of people value music, and can or should that level of value be reflected in music’s economic value? The dramatic decline in the economic value of recorded popular music in the 21st century has prompted much debate about music being ‘devalued’ and the perceived ‘value gap’ between music’s socio-cultural and economic values ...
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Statistical Properties and Applications of k-Record Values Based on the Generalized Lindley Distribution

Journal of Probability and Statistics
This research explores the characteristics and uses of k-record values derived from the generalized Lindley distribution, an adaptable extension of the traditional Lindley distribution.
Maysam Abdulnabi Abdulhasan Al-Saedi, Hossein Jabbari Khamnei, Ali Akbar Heydari, Somayeh Makouei   +3 more
doaj   +1 more source