Results 121 to 130 of about 8,732,171 (340)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Does Quantum Mechanics Require “Conspiracy”?

open access: yesEntropy
Quantum states containing records of incompatible outcomes of quantum measurements are valid states in the tensor-product Hilbert space. Since they contain false records, they conflict with the Born rule and with our observations.
Ovidiu Cristinel Stoica
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Calidad del registro de sintomáticos respiratorios en los laboratorios del municipio de Boyeros

open access: yesRevista Cubana de Higiene y Epidemiología
OBJETIVO: Evaluar la calidad del llenado de un nuevo modelo para el registro de los sintomáticos respiratorios en el laboratorio del Policlínico. MÉTODOS: Se realizó una capacitación sobre el correcto llenado del nuevo documento de registro de los ...
Tamine Jordán Severo   +4 more
doaj  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

New information on the chiropterofauna of Eastern Crimea

open access: yesЮг России: экология, развитие
Aim. Study of the current state of the bat population of Eastern Crimea, features of distribution, occurrence and relative abundance of bats in the region, and monitoring of known colonies in underground cavities of the Kerch Peninsula.The results of ...
A. I. Ivanitzky, A. A. Maslov
doaj   +1 more source

File 1: Financial records, 1967-1983 [PDF]

open access: yes, 1983
Lakeside Orchards Improvement District general financial records, 1967-1983.

core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

State Records - Records relating to Access to records in State Records' custody

open access: yes
Records relating to access to records in State Records ...

core  

Home - About - Disclaimer - Privacy