Results 161 to 170 of about 8,732,171 (340)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Public Records Stored As Digital Images: Policy Statement
This policy establishes the position of the South Carolina Department of Archives and History regarding the use of digital imaging technology for the maintenance of public ...
South Carolina. Archives and Records Management Division
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Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
State Records - relating to conservation
Data for records relating to conservation for records held by State Records of South ...
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Accelerating positive change in electronic records management: headline findings from a major research project [PDF]
, 2011 This article outlines 10 headline findings from a three-year multidisciplinary project, funded by the UK Arts and Humanities Research Council, on electronic records management (ERM). It also presents examples of solutions to try, or to avoid, grounded in
Childs, Sue +2 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Photographs separated from various series in the Action for Soviet Jewry records (4 digital images)
, 1975 Photographs separated from the Series I-X of the Action for Soviet Jewry records. Photographs of Yaakov Khantsis in Boston (separated from Box 3, Folder 4).Digital ImageDigital finding ...
Action for Soviet Jewry
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