Results 61 to 70 of about 372,161 (243)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A Fault Diagnosis Methodology for Gear Pump Based on EEMD and Bayesian Network. [PDF]

open access: yesPLoS ONE, 2015
This paper proposes a fault diagnosis methodology for a gear pump based on the ensemble empirical mode decomposition (EEMD) method and the Bayesian network.
Zengkai Liu   +4 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

A Deep Learning Approach to Powder X‐Ray Diffraction Pattern Analysis: Addressing Generalizability and Perturbation Issues Simultaneously

open access: yesAdvanced Intelligent Systems, 2023
A deep learning (DL)‐based approach for analysis is proposed. Using synthetic XRD data for a DL approach is inevitable due to the lack of real‐world XRD data. There are two main challenges when conducting a DL‐based XRD analysis: generating realistic XRD
Byung Do Lee   +5 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

MONITORING THE DISTRIBUTION OF CRAYFISH IN ENGLAND AND WALES

open access: yesKnowledge and Management of Aquatic Ecosystems, 2002
The distribution of crayfish in England and Wales is described for the period 1997 to 2001 inclusive and is illustrated using a catchment based classification scheme and 10-km square maps.
SIBLEY P. J.   +2 more
doaj   +1 more source

CD-CNN: A Partially Supervised Cross-Domain Deep Learning Model for Urban Resident Recognition

open access: yes, 2018
Driven by the wave of urbanization in recent decades, the research topic about migrant behavior analysis draws great attention from both academia and the government.
He, Xu   +6 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Development of Groundwater Levels Dataset for Chile since 1970

open access: yesScientific Data
Access to accurate spatio-temporal groundwater level data is crucial for sustainable water management in Chile. Despite this importance, a lack of unified, quality-controlled datasets have hindered large-scale groundwater studies.
Héctor Leopoldo Venegas-Quiñones   +6 more
doaj   +1 more source

The Procusto bed and the archival records classification schemes: analysis of the archival records classification code: administrative activities of the National Archives

open access: yes, 2021
The topic of the article is the classification of records, as part of representation and organization studies, and, more specifically, record classification scheme. The schemes for classifying records are prepared mixing several classification principles in the same classificatory structure.
openaire   +1 more source

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