Results 41 to 50 of about 2,559,048 (306)

کاربرد مدارک و اطلاعات پزشکی در تحقیقات از دیدگاه پژوهشگران

open access: yesمدیریت اطلاعات سلامت, 2008
مقدمه: امروزه تحقیقات در علوم مختلف به عنوان ابزاری قدرتمند و شایان توجه جهت ارزیابی آخرین دستاوردهای علمی به كار می‌رود. مهم‌ترین ابزار راه‌گشای محققین در علوم پزشکی برای انجام تحقیقات، مدارك و اطلاعات پزشكی بیماران در بایگانی‌های بیمارستان‌ها می‌باشد ...
Sima Ajami, Faeze Kalbasi, Mahnaz Kabiri
doaj  

Management in the Portsmouth Block Mill, 1803-1812 [PDF]

open access: yes, 2015
The Portsmouth Block Mills’ operations are assessed using archival materials showing staff numbers, hours and work assignments, providing insight into scheduling and workload management, capacity availability and use, and overall facility organization ...
Wilson, James M.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A cost-benefit analysis of document management strategies used at a financial institution in Zimbabwe: A case study

open access: yesSouth African Journal of Information Management, 2013
Background: Choosing a cost-effective document management approach has become a priority to many organisations, especially in view of the rapidly changing technological environment in which information is being created and managed.
Rodreck David   +2 more
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The Role of Provenance Management in Accelerating the Rate of Astronomical Research [PDF]

open access: yes, 2010
The availability of vast quantities of data through electronic archives has transformed astronomical research. It has also enabled the creation of new products, models and simulations, often from distributed input data and models, that are themselves ...
Berriman, G. Bruce, Deelman, Ewa
core   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Academic Elegance in Library and Information Science: Citation Patterns in High-Impact Journals

open access: yesSAGE Open
The cumulative characteristic of science has led to the practice of citation in scientific works. However, citations serve a dual purpose, not only as a means to acknowledge cumulative knowledge but also as a mechanism to substantiate empirical claims ...
Sümeyye Akça
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

چگونه چالش‌های پیاده‌سازی پرونده‌ی الکترونیک سلامت را هموار کنیم؟: یک مطالعه‌ی کیفی در اصفهان

open access: yesمدیریت اطلاعات سلامت, 2014
مقدمه: دورنمای  پرونده‌س الکترونیک سلامت (Electronic Health Record) در جوامع مختلف ثابت نبوده و در عین به همراه داشتن مزایا و فرصت ها، با چالش روبرو است.
Maryam Jahanbakhsh   +2 more
doaj  

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