Results 51 to 60 of about 13,883 (282)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Resilience of health systems in conflict affected governorates of Iraq, 2014–2018

open access: yesConflict and Health, 2021
Objectives The objective of this study was to assess the resilience of health systems in four governorates affected by conflict from 2014 to 2018, and to convey recommendations.
Shaimaa Ibrahim   +6 more
doaj   +1 more source

Beyond the Rule of Law Conditionality: Exploiting the EU Spending Power to Foster the Union's Values

open access: yesEuropean Papers, 2022
(Series Information) European Papers - A Journal on Law and Integration, 2022 7(2), 697-719 | Article | (Table of Contents) I. Introduction. - II. Protecting EU values through ESI funds: The new fundamental rights "enabling conditions".
Marco Fisicaro
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Vaia storm facing the unbearable lightness of forest reporting

open access: yesForest@, 2021
Recently published data on Italian forest removals from FAO and EUROSTAT are still ridden with inaccuracies and underestimation. In this work we show how and why the Italian forestry data collection system is in itself unreliable. This represents a major
Pettenella D   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

The evolution of conditionality in EU financial assistance under the Recovery and Resilience Facility

open access: yesSSRN Electronic Journal, 2023
This article examines a new type of conditionality provided for in the EU’s Recovery and Resilience Fund (RRF). Funding under the RRF is released where ‘milestones’ have been met and this article examines how these milestones have been formulated and applied in relation to the justice systems of three Member States– two at the heart of the rule of law ...
openaire   +2 more sources

Resistance and resilience responses of a range of soil eukaryote and bacterial taxa to fungicide application [PDF]

open access: yes, 2014
The application of plant protection products has the potential to significantly affect soil microbial community structure and function. However, the extent to which soil microbial communities from different trophic levels exhibit resistance and ...
Bending, Gary D.   +5 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

The multilevel governance challenges of NextGenerationEU: the Spanish and Italian decentralised systems viewed through the lens of federalisation

open access: yesRevista Catalana de Dret Públic
The post-COVID-19 panorama presents serious economic and social challenges, prompting the European Union (EU) to allocate extensive funds to its Member States.
Giulia Santomauro
doaj   +1 more source

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