PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Improved Motor Function in Cervical Spinal Cord Injury Following Spinal Cord Stimulation
Spinal cord stimulation (SCS) is a promising therapy for the management of spinal cord injury. Following SCS, this patient experienced a significant reduction in pain and decreased spasticity, which ultimately led to improved upper extremity function.
Michael Suarez +5 more
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Exposures to Elevated Core Temperatures during Football Training: The Impact on Autonomic Nervous System Recovery and Function. [PDF]
Renaghan E +13 more
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Predictive Factors Associated With Dysphagia in Patients With Traumatic Brain Injury [PDF]
Objective To identify early clinical predictors associated with dysphagia and delayed swallowing recovery in patients with traumatic brain injury (TBI).
Shu-Mei Yang +8 more
doaj +1 more source
Internal or External Training Load Metrics: Which Is Best for Tracking Autonomic Nervous System Recovery and Function in Collegiate American Football? [PDF]
Renaghan E +10 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Quarterly; Began with Mar. 31, 2004?; Description based on: Mar. 31, 2004; title from foot of p. 1 (publisher's web site, viewed Nov. 19, 2008).; Latest issue consulted: June 30, 2008 (viewed Nov.
Connecticut Resources Recovery Authority.
core +2 more sources
Comprehensive Postoperative Physiotherapy for Pulmonary Function, Functional Recovery and Quality of Life in a Patient with Pancreatopleural Fistula: A Rare Case Report [PDF]
Pancreatopleural Fistula (PPF) is a rare complication of pancreatitis that occurs approximately in 0.4% of patients characterised by an abnormal communication between the pancreatic duct and the pleural cavity.
Dinkey A Mankad +2 more
doaj +1 more source

