Results 141 to 150 of about 1,549,907 (299)
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Advanced Healthcare Materials, EarlyView.Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
ESTIMATING REVENUE-CAPTURE POTENTIAL ASSOCIATED WITH PUBLIC AREA RECREATION [PDF]
A traditional contingent valuation approach and the “"trip response method"” were examined as potential techniques for measuring public area recreation revenue-capture potential.
Bergstrom, John C. +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan +12 more
wiley +1 more source
EMPIRICAL SPECIFICATION REQUIREMENTS FOR TWO-CONSTRAINT MODELS OF RECREATION DEMAND [PDF]
Theoretical restrictions implied by the two-constraint recreation demand model are developed. The structure necessary to specify empirical models shows that most current models of recreation incorporate time in a manner inconsistent with theory.
Larson, Douglas M., Shaikh, Sabina L.
core +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee +10 more
wiley +1 more source
ESTIMATING THE OPPORTUNITY COST OF RECREATION TIME IN AN INTEGRABLE 2-CONSTRAINT COUNT DEMAND MODEL [PDF]
How researchers treat the opportunity cost of time substantially influences recreation demand parameter and welfare estimates. This paper presents a utility-theoretic and implementable approach, estimating the shadow value of time jointly with recreation
Larson, Douglas M. +2 more
core +1 more source
Advanced Healthcare Materials, EarlyView.An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone +4 more
wiley +1 more source
ON THE PRICE OF RECREATION GOODS AS A DETERMINANT OF MALE LABOR SUPPLY [PDF]
This paper examines whether and how changes in the price of goods consumed in conjunction with leisure time influence the life-cycle allocation of work effort by part of prime-age males.
Jorge González-Chapela
core
Advanced Healthcare Materials, EarlyView.Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez +6 more
wiley +1 more source
Use of Time for Outdoor Recreation in the United States, 1965-2007 [PDF]
This study examines time-use for outdoor recreation during 1965 to 2007. Using data on over 47,000 individuals from six nationally representative time-use surveys, we first document time-use trends between 1965 and 2007.
Siikamäki, Juha
core