Results 51 to 60 of about 1,643,373 (376)

Recreational reluctance [PDF]

open access: yesBritish Dental Journal, 2021
O, Mudhar, M, Agarwala
openaire   +2 more sources

Involvement of Park and Recreation Professionals in Pedestrian Plans [PDF]

open access: yes, 2009
Professionals from many different disciplines are finding innovative ways to work together to increase physical activity to help create healthier communities.
Aytur, Semra   +3 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

The Effect of Recreation in a Snow-Covered Forest Environment on the Psychological Wellbeing of Young Adults: Randomized Controlled Study

open access: yesForests, 2019
Forest recreation can be successfully conducted for the purpose of psychological relaxation, as has been proven in previous scientific studies. During the winter in many countries, when snow cover occurs frequently, forest recreation (walking, relaxation,
E. Bielinis   +5 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

A Study to Evaluate the Recreation Potential of Bentler Nature Park

open access: yesMehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü, 2022
Within the dense population and urbanization, natural areas in the cities are becoming more valuable as places where the recreation needs are met. Natural parks with visual value along with vegetation and wildlife also have an important place among ...
Eren Dağra SÖKMEN, Ş. Doğanay YENER
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

TÜRKİYE’DE 2009-2020 YILLARI ARASINDA ÖĞRETMENLER İLE YAPILAN SERBEST ZAMAN KONULU BİLİMSEL ÇALIŞMALARIN İNCELENMESİ

open access: yesSpormetre Beden Eğitimi ve Spor Bilimleri Dergisi, 2021
Bu araştırmada, 2009-2020 yılları arasında Türkiye’de öğretmenler ile yapılan serbest zaman konulu bilimsel çalışmaların incelenmesi amaçlanmıştır. Araştırmada, nitel araştırma yöntemlerinden biri olan içerik analizi tekniği kullanılmıştır.
Gözde Yetim, Fatih Mirze
doaj   +1 more source

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