Results 51 to 60 of about 358,165 (279)

Two-year retrospective analysis of patients undergoing direct to procedure flexible sigmoidoscopy investigation with rectal bleeding as a primary complaint

Endoscopy International Open, 2018
Background and aims Rectal bleeding affects ~15 % of the general population and is a common reason for referral to gastroenterologists by primary care physicians.
Henry H. Nguyen, Robert Bechara, William G. Paterson, Lawrence C. Hookey   +3 more
doaj   +1 more source

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang, Xin‐Rong Xu, Hui‐Lin Zhang, Qi‐Meng Zhu, Xin‐Yuan Li, Xi‐Peng Shang, Jing‐Hui Du, Christophe Morisseau, Feng Qiu, Cheng‐Peng Sun   +9 more
wiley   +1 more source

Indwelling Bowel Management System as a Cause of Life-Threatening Rectal Bleeding

Case Reports in Gastroenterology, 2008
A 79-year-old male was transferred to the intensive care unit for postoperative respiratory support. An indwelling bowel management system was inserted for containment of noninfective diarrhoea.
Elizabeth Bright, Guy Fishwick, David Berry, Michael Thomas   +3 more
doaj   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Colonoscopic examination of rectal bleeding in children: A report of two cases

African Journal of Paediatric Surgery, 2012
Rectal bleeding in children is a frightening and cause of great concern, and of parental anxiety. In this report, we present the value of colonoscopy to unravel the diagnostic conundrum often associated with rectal bleeding in children.
Abdulfatai B Olokoba, Olusegun A Obateru, Mathew O Bojuwoye, Olatunde K Ibrahim, Olasunkanmi M Babalola   +4 more
doaj   +1 more source

Balloon-occluded antegrade transvenous obliteration of rectal varices: A case report

Radiology Case Reports, 2021
Patients with liver cirrhosis frequently experience rectal variceal bleeding subsequent to portal hypertension. Unlike gastroesophageal variceal bleeding, a well-established guideline does not exist in terms of management of bleeding rectal varices. A 75-
Alireza Abrishami, MD, MBA, Arezou Hashem Zadeh, MD, Nastaran Khalili, MD-MPH, Hadi Rokni Yazdi, MD   +3 more
doaj   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Endoscopic ultrasound–guided coil embolization and absorbable hemostatic gelatin sponge is a safe and efficacious treatment for bleeding rectal varices

iGIE
Background and Aims: Rectal variceal bleeding is a rare life-threatening cause of lower gastrointestinal bleeding. We present the first case series to our knowledge of successful hemostasis achieved with combination of endoscopic ultrasound (EUS)-guided ...
Kanwal Bains, MD, Thomas J. Wang, MD, Marvin Ryou, MD   +2 more
doaj   +1 more source

Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer - Preliminary results [PDF]

, 2003
Background: The local recurrence rate of colorectal cancer has been significantly reduced due to the use of combined radiochemotherapy. Despite this improvement regarding locally advanced tumour recurrences, the treatment strategy for pre-treated ...
Schaffer, P.M., Ertl-Wagner, Birgit, M. Schaffer, E. Dühmke, P.M. Schaffer, R.D. Issels, Pachmann, S., Abdel-Rahman, Sultan, S. Abdel-Rahman, Abdel-Rahman, S., Ertl-Wagner, B., Krych, M., Issels, Rolf-Dieter, Dühmke, E., B. Ertl-Wagner, Schaffer, Pamela Manuela, M. Krych, S. Pachmann, Schäffer, M., Issels, R.D., Dühmke, Eckhart, Schaffer, Moshe   +21 more
core   +1 more source

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source