Results 161 to 170 of about 2,337,549 (294)

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

Gut Colonisation and Multidrug-Resistant Urinary Tract Infections in Hospitalised Kidney Transplant Recipients: A Single-Centre Retrospective Study. [PDF]

Antibiotics (Basel)
Loiacono L, Navarra A, Rotondo C, Dimartino V, Iacomi F, Abdeddaim A, Lionetti R, Paolis P, Fontana C, Biliotti E, D'Offizi G.   +10 more
europepmc   +1 more source

Impact of extended insurance coverage on survival outcomes among patients with metastatic colorectal cancer in Taiwan

British Journal of Clinical Pharmacology, EarlyView.
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang, Chen‐Han Chueh, Chien‐Yu Tseng, Christopher N. Kaufmann, Earl J. Morris, Chiao‐En Wu, Yi‐Wen Tsai   +6 more
wiley   +1 more source

Rectal Surveillance for Carbapenem-Resistant <i>Klebsiella pneumoniae</i>: Prevalence and Clinical Relevance in a Multidisciplinary Tertiary-Care Hospital. [PDF]

Antibiotics (Basel)
Penea CAO, Melinte V, Crețu E, Holban T, Radu AM, Vacaroiu CM, Cambrea CS, Gheorghiță V.   +7 more
europepmc   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Rectal Dieulafoy Lesion with Severe Hematochezia in a Warfarin-Treated Patient. [PDF]

J Community Hosp Intern Med Perspect
Alatorre CE, Rubianes Guerrero MG, Valencia Manrique JC, Harley J.   +3 more
europepmc   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Performance of an Electronic Sentinel Surveillance System for Bacterial Gastroenteritis: Mixed Methods Evaluation Study. [PDF]

JMIR Public Health Surveill
Song I, Heo Y, Jo M, Park JY, Ryu S, Kim DS.   +5 more
europepmc   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source

Reply to Gupta, "Reconsidering throat swab culture in melioidosis: diagnostic stewardship with clinical nuance". [PDF]

J Clin Microbiol
Duguid RC, Baird RW, Hennessy J, Currie BJ, Meumann EM.   +4 more
europepmc   +1 more source