Results 181 to 190 of about 168,609 (265)

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

open access: yesJournal of Evidence-Based Medicine, Volume 19, Issue 3, September 2026.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li   +7 more
wiley   +1 more source

Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)

open access: yesJournal of Evidence-Based Medicine, Volume 19, Issue 3, September 2026.
ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li   +6 more
wiley   +1 more source

Perioperative Transfusion Trigger Score Versus Restrictive Transfusion in Older Non‐Cardiac Surgery Patients: A Multicenter Randomized Controlled Trial

open access: yesJournal of the American Geriatrics Society, Volume 74, Issue 9, Page 2564-2572, September 2026.
ABSTRACT Background Restrictive transfusion (Hb < 7 g/dL) is recommended for most perioperative patients, but the optimal threshold for those with cardiovascular disease or Hb 7–10 g/dL remains uncertain. The Perioperative Transfusion Trigger Score (POTTS), which integrates adrenaline requirement, FiO2, temperature, and angina history, may standardize ...
Shucong Liang   +9 more
wiley   +1 more source

Application of Three‐Dimensionally Printed Surgical Guides in Precise Sacral Tumor Excision and Defect Reconstruction

open access: yesOrthopaedic Surgery, Volume 18, Issue 9, Page 1847-1860, September 2026.
Patient‐specific 3D‐printed guiding templates significantly improve surgical precision and efficiency in complex sacral tumor resection and reconstruction compared to conventional freehand techniques. This computer‐assisted workflow reduces operative time, intraoperative blood loss, and fluoroscopy frequency, providing a safer, highly reproducible ...
Yansong Liu   +7 more
wiley   +1 more source

Physiological cerebrospinal fluid interactions between brain and eye structures are altered after long‐duration spaceflight

open access: yesExperimental Physiology, Volume 111, Issue 9, Page 4209-4222, 1 September 2026.
Abstract Long‐duration spaceflight represents an extreme challenge, triggering adaptive responses including spaceflight‐associated neuro‐ocular syndrome, characterized by diminished visual acuity and ocular changes, which is a significant health risk for Mars missions.
Ge Tang   +19 more
wiley   +1 more source

Impaired peri‐infarct long‐term potentiation in anaesthetized rats suggests alternative mechanisms of post‐stroke recovery

open access: yesThe Journal of Physiology, Volume 604, Issue 18, Page 7819-7844, 15 September 2026.
Abstract figure legend It is hypothesized that a period of heightened structural plasticity in the peri‐infarct area, triggered early after stroke, opens a time window of heightened capacity for long‐term potentiation (LTP) during which the brain becomes more responsive to rehabilitation training.
Clément Vitrac   +3 more
wiley   +1 more source

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