Results 111 to 120 of about 549,282 (362)

Use of rectal mucosal grafts in substitution urethroplasty: an early series [PDF]

, 2018
Background: To evaluate the feasibility of use of rectal mucosal grafts for augmentation urethroplasty. Methods: A series of five patients who underwent rectal mucosal graft urethroplasty for urethral stricture disease were identified. Descriptive
Mellon, Matthew J., Monn, M. Francesca, Waters, Joshua A.   +2 more
core   +1 more source

ACSS2‐Mediated Histone H4 Lysine 12 Crotonylation (H4K12cr) Alleviates Colitis via Enhancing Transcription of CLDN7

Advanced Science, EarlyView.
Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan, Shaopeng Chen, Zhensen Lin, Runfeng Yu, Kang Chao, Shubiao Ye, Qing Li, Haoxian Ke, Chi Zhang, Junfeng Huang, Guanzhan Liang, Tuo Hu, Xiang Gao, Ping Lan, Xianrui Wu   +14 more
wiley   +1 more source

Metastasis of Rectal Signet Ring Cell Carcinoma to Typical Lipoma: A Rare Presentation of the Tumor-to-Tumor Metastasis Phenomenon

Journal of Investigative Medicine High Impact Case Reports
Rectal signet ring cell carcinoma represents a rare subtype of colorectal adenocarcinoma known for its aggressive biological nature and poor prognosis. Although the co-occurrence of colorectal carcinoma with other tumors has been reported, the uncommon ...
Houyem Mansouri MD, Ines Zemni MD, Nedia Boujelbene MD, Fatma Saadallah MD, Mohamed Ali Ayadi MD, Leila Achouri MD   +5 more
doaj   +1 more source

Characterization and prognostic value of mutations in exons 5 and 6 of the p53 gene in patients with colorectal cancers in central Iran [PDF]

, 2013
Background/Aims: We aimed to investigate the relation-ships among various mutations of the p53 gene and their protein products, histological characteristics, and disease prognosis of primary colorectal cancer in Isfahan, central Iran.
Anwar, Bazan, Carson, Chang, Chang, Coombs, Cunningham, Derakhshan, Diez, Duffy, Erster, Gryfe, Hollstein, Jemal, Karsa, Kato, Lam, Leahy, Levine, Lim, Mahdavinia, Markowitz, Mehdi Nikbakht, Mohammad H. Derakhshan, Mohammad J. Namazi, Mohammad Salehi, Molleví, Mousavi, Munro, Nasierowska-Guttmejer, Nunes, Pan, Rahim Golmohammadi, Rogel, Russo, Ryan, Sadjadi, Schmitt, Slattery, Tang, Theodoropoulos, Tominaga, Vogelstein, Yamashita, Yee, Zhang, Zhao   +46 more
core   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source

Large Friable Rectal Neuroendocrine Tumor Complicated by Hemorrhagic Shock: A Rare Case Report and Review of the Literature

JGH Open
Rectal neuroendocrine tumors (NETs) are rare neoplasms that are usually asymptomatic and diagnosed incidentally. There are limited data on the presentation and management of high‐grade poorly differentiated large friable rectal NETs.
Yazan Abboud, Imran Qureshi, Ayham Khrais, Alexander Le, Param Patel, Ozlem Fidan Ozbilgin, Sima Vossough‐Teehan   +6 more
doaj   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Neuroendocrine Rectal Tumors: Main Features and Management

GE: Portuguese Journal of Gastroenterology, 2015
The incidence of neuroendocrine tumors of the rectum has been increasing in the last decades, partly due to improved investigation. They are mostly well-differentiated small tumors with a rather good overall prognosis. In the last few years, some aspects
Ângela Rodrigues, Fernando Castro-Poças, Isabel Pedroto   +2 more
doaj   +1 more source

STRAIN ELASTOGRAPHY AS DIAGNOSTIC TOOL FOR EVALUATION OF RECTAL NEOPLASMS

, 2017
AIM. To establish cut-off point of strain ratio for rectal adenocarciomas. PATIENTS AND METHODS. Forty-five patients (29 female) at mean age ± SD of 61 ± 9.5 (range, 38-80) years with histologically confirmed rectal neoplasia were included into study ...
Y. Shelygin, L. Orlova, T. Samsonova, O. A. Majnovskaja, S. Chernyshov, E. M. Abashina, P. G. Evgrafov, E. Rybakov   +7 more
semanticscholar   +1 more source

Surgical treatment of high-lying rectal neoplasms

Kazan medical journal, 1934
Currently, the dominant surgical interventions for high-lying rectal neoplasms are intraperitoneal and sacral methods. The latter methods, which are well established, have a great statistical record both in our Union and among surgeons in the West and America. However, we cannot say that we are completely satisfied with these methods: peritoneal-sacral
A. A. Kudryavtsev, Ya. M. Iofan
openaire   +2 more sources