Results 111 to 120 of about 582,867 (329)
Advanced Science, EarlyView.An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou +30 more
wiley +1 more source
A novel combination of triple metachronous malignancies of the kidney, oropharynx and prostate. A case report [PDF]
, 2015 Synchronous or metachronous malignancies are a rare event, with an incidence rate that increases with age. The present study reports the case of a 70-year-old Caucasian male who was referred to the outpatient office of the Urology Unit, Sapienza ...
Carbone, Antonio +6 more
core +1 more source
, 2015 Impact of technology on indications and limitations for transanal surgical removal of rectal ...
B. Devaraj, A. Kaiser
semanticscholar +1 more source
Multiscale Construction, Evaluation, and Application of Organoids
Advanced Science, EarlyView.Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma +5 more
wiley +1 more source
Advanced Science, EarlyView.A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding +11 more
wiley +1 more source
A Comprehensive Analysis of 174 Febrile Patients Admitted to Okayama University Hospital [PDF]
, 2013 Primary care physicians often encounter patients with fever of unknown origin and without apparent causes. Recent advances in laboratory medicine have facilitated diagnostic procedures;however, it is still difficult to determine the critical febrile ...
Otsuka, Fumio, Ryuko, Hiromasa
core +1 more source
Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1
Advanced Science, EarlyView.This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu +20 more
wiley +1 more source
Neuroendocrine Rectal Tumors: Main Features and Management
GE: Portuguese Journal of Gastroenterology, 2015 The incidence of neuroendocrine tumors of the rectum has been increasing in the last decades, partly due to improved investigation. They are mostly well-differentiated small tumors with a rather good overall prognosis. In the last few years, some aspects
Ângela Rodrigues +2 more
doaj +1 more source
The role of endoscopic ultrasonography in the management of cystic lesions of the pancreas [PDF]
, 2003 Objective. To review the role of endoscopic ultrasonography in the management of cystic lesions of the pancreas. Data sources. MEDLINE literature search (1998-2003). Study selection. Key words for the literature search were 'endoscopic ultrasonography', '
Chan, ACY, Liu, CL
core