Results 161 to 170 of about 280,810 (293)

Fertility counseling and preservation considerations in patients with gynecologic and non‐gynecologic BRCA and Lynch‐associated malignancies

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Lynch syndrome and BRCA‐mutation associated malignancies are fortunately rare. Affected patients have an increased risk of cancer diagnosis at a young age, often significantly overlapping with their reproductive years. In helping these patients, oncologists must navigate the following areas of care: cancer prevention, impact of cancer ...
Anna Weimer, Nadeem Abu‐Rustum, David Mutch, Mauricio Cuello, Angélica Fletcher, Hextan Y. S. Ngan, Nozomu Yanaihara, Rene Pareja, Christina Fotopoulou, Kenneth Ruzindana, Ka Yu Tse, Yana Zou, Neerja Bhatla, Ting‐Chang Chang, Munanchiso Ndukwe Iheme Jr, Jalid Sehouli, Nicole Conchin, Eva Chalas, Sarikapan Wilailak, Barbara Schmalfeldt, Alexander B. Olawaiye   +20 more
wiley   +1 more source

Long‐Read Pan‐Cancer Transcriptomics Unravel Distinct Alteration Trends Between Gene and Isoform Expression in Tumorigenesis

iMetaMed, EarlyView.
Long‐read profiling of 144 tumor‐normal pairs identifies isoform‐level cancer dysregulation independent of gene changes. Our scoring system prioritizes isoform‐driven prognostic genes across cancers. ABSTRACT Tumorigenesis involves transcriptomic alterations at both gene and isoform levels.
Yuying Ding, Bo Wu, Dan Zhou, Qiang Li, Dingru Li, Mengyun Cai, Zhiyan Chen, Caimei Zhong, ChuanLe Xiao, Yuhua Deng   +9 more
wiley   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

iMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang, Jinfei Liu, Qiangsheng Wang, Lei Fan, Ziang Li, Xuexin Yu, Yonghao Chen, Xiaofan Lu, Guiyi Liao, Jialin Meng, Yu Guan   +10 more
wiley   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

Advancements and prospects in bioinformatics and omics for colorectal cancer: A dual bibliometric analysis of global trends and top cited publications

Journal of Intelligent Medicine, EarlyView.
This dual bibliometric analysis examined 5129 publications and the top 100 most cited publications on bioinformatics and omics in colorectal cancer (2004–2025) from the Web of Science Core Collection. Using SCImago Graphica, VOSviewer, CiteSpace, and R Studio, we analyzed global trends, countries/regions, institutions, journals, authors, references ...
Yue Huang, Ziye Peng, Xiangyu Wang, Likun Yang, Yifei Gao, Ximo Wang, Jiaxin Li, Zhengcun Pei   +7 more
wiley   +1 more source

Rectal schwannoma mimicking malignant rectal cancer: a case report. [PDF]

Int J Surg Case Rep
Negahi A, Tabaeian SP, Babaheidarian P, Kamali R.   +3 more
europepmc   +1 more source

Dosimetric Outcomes of Definitive Radiation Therapy to Anal Squamous Cell Carcinoma in a Single Institution Using Volumetric Modulated Arc Therapy Evaluated Against Australian and International Treatment Planning Guidelines

Journal of Medical Radiation Sciences, EarlyView.
This study evaluated 43 clinically approved VMAT plans for anal squamous cell carcinoma (SCC) against RTOG, eviQ, ANROTAT and departmental planning guidelines to assess the achievability of current dose constraints. While most target coverage and median OAR dose objectives were within protocol, not all constraints were consistently met, supporting the ...
Faisal Alshamrani, Michael Hsieh, Anthony Karl, Lauren Chamberlain, Stuart Greenham, Josie Goodworth, Maree Wood, Thomas Shakespeare, Tue Le, Abdul Mohd Tahir   +9 more
wiley   +1 more source

Risk Factors for Microscopically Non-radical Surgical Resection in Patients With Rectal Cancer Undergoing Neoadjuvant Radiotherapy. [PDF]

In Vivo
Valdimarsson V, Dahlbäck C, Buchwald P.
europepmc   +1 more source

Deep Learning and Machine Learning Algorithms for Cervical Cancer Segmentation on MRI: A Systematic Review

Journal of Medical Radiation Sciences, EarlyView.
This systematic review summarizes current evidence on machine and deep learning algorithms for MRI‐based cervical cancer segmentation, demonstrating promising diagnostic performance and potential for workflow automation. However, methodological heterogeneity, limited external validation, and low certainty of evidence highlight the need for standardized
Somayeh Haji Ahmadi, Sina Soltan Mohammadi, Abolfazl Koozari, Mohammadreza Elhaie   +3 more
wiley   +1 more source