Results 201 to 210 of about 263,943 (292)

Schisandrin C Targets PPARγ to Induce Ferroptosis in Colorectal Cancer Cells and Promote M1 Macrophage Polarization

open access: yesPhytotherapy Research, EarlyView.
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei   +4 more
wiley   +1 more source

Impact of general anaesthesia on immune response to first rabies vaccination in seronegative domestic cats

open access: yesVeterinary Record, EarlyView.
Abstract Background Despite common concerns, evidence that anaesthesia impairs vaccine efficacy remains limited. This study assessed the impact of general anaesthesia on the immune response to rabies vaccination in cats. Methods Thirty‐five healthy female cats (6–12 months old) undergoing elective spaying were enrolled.
Pierre Bessière   +8 more
wiley   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

open access: yesVIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao   +8 more
wiley   +1 more source

Does Subspecialization Matter? Institutional Outcomes Before and After Recruitment of Colorectal Surgeons

open access: yesWorld Journal of Surgery, EarlyView.
Colorectal surgery fellowship is one of the most sought‐after subspecialty programs among general surgery residents, yet most colon and rectal surgeries are performed by general surgeons without specialized training. This study evaluated whether integrating fellowship‐trained colorectal surgeons (CRS) into a general surgery department is associated ...
Amram Kupietzky   +7 more
wiley   +1 more source

Tumor count and risk of lymph node metastasis in multiple rectal neuroendocrine tumors: an individual-level pooled analysis. [PDF]

open access: yesWorld J Surg Oncol
Xu J   +10 more
europepmc   +1 more source

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