Results 41 to 50 of about 123,237 (218)

Multidisciplinary approach to the treatment of concomitant rectal and vaginal prolapse

open access: yes, 2019
Rectal prolapse and vaginal prolapse have traditionally been treated as separate entities despite sharing a common pathophysiology. This compartmentalized approach often leads to frustration and suboptimal outcomes.
Gurland, Brooke, Jallad, Karl
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Surgical Techniques for Rectal Prolapse

open access: yes, 2021
Complete rectal prolapse or rectal procidentia is a debilitating disease that presents with fecal incontinence, constipation, and rectal discharge. Definitive surgical techniques described for this disease include perineal procedures such as mucosectomy ...
Sezai Leventoglu   +7 more
core   +1 more source

Complete rectal prolapse presenting with colorectal cancer

open access: yesInnovative Surgical Sciences, 2023
Rectal prolapse is defined as prolapse of all layers of rectal wallout of the anal sphincter. The aim was to (i) describe the extremely rare combination of a rectal prolapse with colon cancer in an older female patient, (ii) comment on management ...
Perrakis Aristoteles   +2 more
doaj   +1 more source

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula   +8 more
wiley   +1 more source

Human evolution and the obstetrical dilemma: The pelvic floor hypothesis

open access: yesThe Anatomical Record, EarlyView.
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley   +1 more source

c-Abl regulates gastrointestinal muscularis propria homeostasis via ERKs

open access: yesScientific Reports, 2017
The gastrointestinal tract is responsible for food digestion and absorption. The muscularis propria propels the foodstuff through the GI tract and defects in intestine motility may cause obstruction disorders.
Jinnan Xiang   +11 more
doaj   +1 more source

The use of laparoscopic rectopexy to manage rectal prolapse with Pseudo‐Meigs’ syndrome in a 64‐year‐old female: a case report

open access: yesClinical Case Reports, 2017
Key Clinical Message We report a rare case of rectal prolapse with Pseudo‐Meigs’ syndrome in which laparoscopic bilateral oophorectomy and rectopexy were performed simultaneously and resulted in improved quality of life due to the loss of ascites and the
Takayuki Kondo   +6 more
doaj   +1 more source

History of the Treatment of Rectal Prolapse. [PDF]

open access: yesClin Colon Rectal Surg
Rectal prolapse is the intussusception of the rectum, resulting in its full-thickness protrusion out of the anus. Approximately 0.5% of the general population is affected by this condition, with a higher occurrence in women and the elderly. While benign,
Spivak R, Hu K.
europepmc   +2 more sources

Rectopexy for Rectal Prolapse [PDF]

open access: yesFrontiers in Surgery, 2015
Ventral mesh rectopexy (VMR) is a recognized treatment for posterior compartment pelvic organ prolapse (POP). The aim of this review is to provide a synopsis of the evidence for biological mesh use in VMR, the most widely recognized surgical technique for posterior compartment POP.A systematic search of PubMed was conducted using the search terms "VMR,"
Alam, Nasra N   +4 more
openaire   +4 more sources

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