Results 131 to 140 of about 163,408 (302)

From DNA Methylation Microarray to Digital PCR: A Stepwise Strategy for Tissue Specific cfDNA Biomarker Development

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Overview of a DNA methylation biomarker development pipeline, from discovery and assay design to screening, performance evaluation, and specificity testing in clinical sample matrices. ABSTRACT Background Tissue‐specific cell‐free DNA (cfDNA) offers promise as a minimally invasive biomarker of organ injury.
David H. Murray   +6 more
wiley   +1 more source

Comparison of infrared thermography of the blowhole mucosa with rectal temperatures in killer whales (Orcinus orca)

open access: yesFrontiers in Marine Science
Killer whales are an important sentinel species and developing non-invasive methods of health assessments might provide insight for understanding how wildlife health is influenced by ecosystem change.
Jennifer P. Russell   +7 more
doaj   +1 more source

Immunological and periodontal benefits of prebiotic polydextrose in rats with induced periodontitis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Prebiotic therapy is a promising approach for managing periodontitis due to its potential benefits in modulating the microbiome and the immune response. This study aimed to evaluate the effects of the prebiotic (PREB) polydextrose (PDX) on the development of experimental periodontitis (EP) in rats.
Raquel de S. F Nassar   +9 more
wiley   +1 more source

Using Thermal Signature to Evaluate Heat Stress Levels in Laying Hens with a Machine-Learning-Based Classifier

open access: yesAnimals
Infrared thermography has been investigated in recent studies to monitor body surface temperature and correlate it with animal welfare and performance factors.
Isaac Lembi Solis   +4 more
doaj   +1 more source

Dehydration stress associated variations in rectal temperature, pulse and respiration rate of Marwari sheep [PDF]

open access: yes, 2013
The present investigation was carried out in adult female Marwari sheep to evaluate the dehydration stress associated variations in rectal temperature, pulse and respiration rate.
Kataria, A. K.   +3 more
core  

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri   +7 more
wiley   +1 more source

Thermoregulation During Spaceflight [PDF]

open access: yes
The purpose of this flight proposal is to investigate human thermoregulatory parameters during exercise in microgravity. The hypothesis to be tested is that microgravity-adopted astronauts will exhibit accentuated increases in their core temperature ...
Fortney, Suzanne M., Greenleaf, John E.
core   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

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