Results 191 to 200 of about 163,408 (302)

Benefits and Harms of Antenatal/Intrapartum Screening for Maternal Group B Streptococcus and Use of Intrapartum Antibiotic Prophylaxis Versus Risk‐Based Protocols or No Intervention: A Rapid Review

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To synthesise evidence on the effectiveness, harms and benefits of different approaches to prevent early‐onset Group B Streptococcus (EOGBS) and identify gaps in short and longer‐term outcomes. Methods A two‐phase rapid review. Phase 1 included an overview of systematic reviews (SRs).
Pauline Campbell   +12 more
wiley   +1 more source

Paracetamol prescribing to small animals by veterinarians in Australia and New Zealand

open access: yesAustralian Veterinary Journal, EarlyView.
Objective To describe the prescribing patterns of paracetamol by veterinarians in Australia and New Zealand. Methods An online survey was created and distributed to veterinarians in Australia and New Zealand over a 3‐month period (July–October 2024).
A Tse, W Chee, CJ Boyd, CR Sharp
wiley   +1 more source

Focal therapy using a novel cooled laser device for prostate cancer: early trial results

open access: yesBJU International, EarlyView.
Objectives To determine the short‐term oncological results and safety of the ProFocal Laser Therapy for Prostate Tissue Ablation (PFLT‐PC) trial, the first phase II clinical trial of ProFocal® (Medlogical Innovations, Sydney, Australia), a novel, cooled laser focal therapy (cLFT) device for prostate cancer (PCa) treatment. Patients and Methods Men with
Jonathan Kam   +17 more
wiley   +1 more source

Diaphragm‐specific effects of L‐citrulline in mdx mice highlight its potential as adjuvant of standard therapy in Duchenne muscular dystrophy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The absence of the protein dystrophin in Duchenne muscular dystrophy (DMD) leads to progressive muscle weakness, failing regeneration and deregulation of nitric oxide (NO) signalling. We focused on L‐citrulline, a precursor of L‐arginine, required for NO production in muscle, which is reduced in dystrophic mdx muscle ...
Lisamaura Tulimiero   +14 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci   +15 more
wiley   +1 more source

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