Results 31 to 40 of about 93,203 (252)

Comparison of Digital Rectal Thermometry and a Non-Contact Veterinary Infrared Thermometer in Cats: Identifying Alternative Sites to Rectal Measurement

Veterinary Sciences
Background: Rectal temperature measurement in cats, while crucial, can cause discomfort and stress. This study evaluated non-contact infrared thermometry as a less invasive alternative. Methods: A total of 95 cats were enrolled in this study.
Carlotta Tombolani, Daniela Alberghina, Mauro Gioè, Fausto Quintavalla   +3 more
doaj   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

So, what's best? Accuracy and acceptance of thermometers in triage and inpatients in a low-resource tropical setting – The MaTe study

Heliyon
Objectives: We searched for the most-suitable thermometry method in the low-resource, tropical setting of Sierra Leone, both in terms of accuracy and also patient and user acceptance.
Alexandra Turnbull, Harry Putnam, Issa Sesay, Aminata Bangura, Emily Bailey, Jan Henk Dubbink, Martin P. Grobusch   +6 more
doaj   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Oral and Tympanic Membrane Temperatures are Inaccurate to Identify Fever in Emergency Department Adults

Western Journal of Emergency Medicine, 2011
Introduction: Identifying fever can influence management of the emergency department (ED) patient, including diagnostic testing, treatment, and disposition.
Robert Silverman, Richard Powell, Patricia Nichols, Vladmir Fridman, Martin Lesser, Julia Tai, Stacy Nunberg, Barbara J Barnett   +7 more
doaj  

Forehead or ear temperature measurement cannot replace rectal measurements, except for screening purposes

BMC Pediatrics, 2018
Background Measuring rectal temperature in children is the gold standard, but ear or forehead measures are less traumatic and faster. The quality of non-invasive devices has improved but concerns remain whether they are reliable enough to substitute ...
Christian Backer Mogensen, Lena Wittenhoff, Gitte Fruerhøj, Stephen Hansen   +3 more
doaj   +1 more source

Rectal Temperature of Corpse and Estimation of Postmortem Interval [PDF]

Fayixue Zazhi, 2019
Measurement of corpse temperature is mainly used for estimation of early postmortem interval, and rectal temperature is often used as a representative of body’s core temperature in actual work because it is simple, quick and non-invasive. At present, the
YANG An-shun, QUAN Guo-lin, GAO Yun-gui,et al.
doaj   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

A comparison of tympanic and rectal temperatures in term NIGERIAN neonates

BMC Pediatrics, 2012
Background Tympanic thermometry has come as a suitable alternative to traditional thermometry because of its safety and ease of use. However, it is still yet to gain wide acceptance in African settings due to conflicting results on its accuracy, thus ...
Duru Chika O, Akinbami Felix O, Orimadegun Adebola E   +2 more
doaj   +1 more source