Results 251 to 260 of about 5,081,991 (350)

Erratum: Safety and feasibility of laparoscopic intersphincteric resection for a lower rectal tumor. [PDF]

Oncol Lett, 2018
Matsuhashi N, Takahashi T, Tanahashi T, Matsui S, Imai H, Tanaka Y, Yamaguchi K, Osada S, Yoshida K.   +8 more
europepmc   +1 more source

Molecular, spatial, and AI‐enabled technologies for predicting neoadjuvant therapy response in locally advanced rectal cancer

The Journal of Pathology, EarlyView.
Abstract Pretreatment prediction of neoadjuvant response remains an unresolved challenge in locally advanced rectal cancer, where management is moving towards risk‐adapted and response‐oriented treatment strategies. Prediction remains difficult because response reflects interacting tumour‐intrinsic, immune, stromal, and spatial processes that are ...
Gina F Boot, Cibele Masotti, Claudia Corrò, Cédric Schraepen, Hannah L Williams, Thomas A Wright, Fiza Ishaqwala, Colin W Steele, Gertjan Rasschaert, Maxime W Lafarge, Enric Domingo, Inti Zlobec, Rodrigo Oliva Perez, Campbell SD Roxburgh, Timothy S Maughan, Sabine Tejpar, Thibaud Koessler, Viktor H Koelzer   +17 more
wiley   +1 more source

Expert consensus on clinical trial design guidelines for FLASH radiotherapy

Precision Radiation Oncology, EarlyView.
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo, Chen Cheng, Chengliang Yang, Bing Li, Jiandong Zhang, Jinbo Yue, Zhaoyang Lou, Hui Liu, Jing Cai, Hong Ge   +9 more
wiley   +1 more source

Feasibility of Urethra‐Sparing Ultra‐Hypofractionated Three‐Dose‐Level Radiotherapy for Prostate Cancer with a Dominant Intraprostatic Lesion Abutting the High‐Dose Avoidance Zone

Precision Radiation Oncology, EarlyView.
Ultra‐hypofractionated three‐dose‐level radiotherapy allows safe dose escalation to dominant intraprostatic lesions near the urethra while maintaining full coverage of pelvis and prostate and respecting urethral and organ‐at‐risk constraints. Abstract This planning study evaluated ultra‐hypofractionated three‐dose‐level radiotherapy for prostate cancer
Annalisa Muscato, Denis La Fauci, Anna Viola, Valentina Zagardo, Gianluca Ferini   +4 more
wiley   +1 more source

Evaluation of Concordance between Radiation Therapists and Medical Physicists in MR‐Guided Online Adaptive Planning

Precision Radiation Oncology, EarlyView.
Magnetic resonance (MR)‐guided online adaptive radiotherapy requires skill in online adaptive treatment planning. This study demonstrated that radiation therapists, with appropriate training, can consistently produce high‐quality adaptive plans concordant with those created by medical physicists for treatment on a 1.5 Tesla MR‐Linac.
Eva Birring, Yao Zhao, Tze Yee Lim, Mustefa Mohammedsaid, Neil Hughes, Cameron Tharp, JaRhonda Tealer, Ruitao Lin, Comron Hassanzadeh, C. David Fuller, Jinzhong Yang   +10 more
wiley   +1 more source

Exploratory Analysis of Peri‐Prostatic Adipose Tissue Radiomics Features and Their Potential to Predict Prostate Cancer Diagnosis: Results From a UK Biobank Study

The Prostate, EarlyView.
ABSTRACT Introduction This paper reports the development and application of an artificial intelligence (AI)–led approach to large volume MRI data curation and image segmentation of periprostatic adipose tissue (PPAT) in prostate cancer (PCa)–free men from the UK Biobank. We report how PPAT was defined, radiomics features of PPAT extracted, and explored
Angela O'Neill, Ryan O'Keeffe, Sarah Winter, Jade Dorrian, Tom R. Gaunt, Vilmundur Guönason, Ruth C. Travis, Richard M. Martin, Emma H. Allott, Michelle Leech   +9 more
wiley   +1 more source

Comparison of Gene Enrichment Between Prostate Tissue and Urine for Non‐Invasive Biomarker Development

The Prostate, EarlyView.
ABSTRACT Background For prostate cancer (PCa), early diagnosis and biomarker‐based patient stratification can improve clinical decision‐making and post‐treatment prognosis. PCa biomarkers are best validated in tissue following comprehensive histopathologic review; however, urinary biomarkers can be obtained non‐invasively and are therefore safer and ...
Yuandong Xing, Minqi Xu, Dan Dion, Vanessa F. Bratti, Ania A. Namin, D. Robert Siemens, Palak G. Patel, Robert J. Gooding, Jane Bayani, Hamid Ghaedi, Anna Y. Lee, David M. Berman   +11 more
wiley   +1 more source

Urinary Soluble Collagen Levels Are Associated With Moderate/Severe LUTS

The Prostate, EarlyView.
ABSTRACT Background Expansion of the stromal compartment of the prostate concurrent with fibroblast activation and increased collagenization is now recognized as a pathobiology likely contributing to Lower Urinary Tract Symptoms (LUTS). However, approaches to quantitatively and, ideally, non‐invasively, assess prostatic collagenization in vivo are not ...
Marissa Sarna‐McCarthy, Claweens Quetant, Quentin D'Arcy, Richard Caesar, Kourosh Zarringhalam, Jill A. Macoska   +5 more
wiley   +1 more source

Risk Factors for Microscopically Non-radical Surgical Resection in Patients With Rectal Cancer Undergoing Neoadjuvant Radiotherapy. [PDF]

In Vivo
Valdimarsson V, Dahlbäck C, Buchwald P.
europepmc   +1 more source

Circulating Tumor Cell Synaptophysin and Androgen Receptor Expression Reflect Prostate Cancer Phenotypes in Metastatic Disease

The Prostate, EarlyView.
ABSTRACT Background Chronic exposure to androgen receptor (AR)‐targeted therapies can drive lineage plasticity, leading to treatment resistance and neuroendocrine prostate cancer (NEPC), characterized by loss of AR expression and acquisition of neuroendocrine (NE) markers including synaptophysin (SYP). We evaluated concordance between circulating tumor
Ethan Lo, Alisa Clein, Michael Tam, Sara Trimble, Michael Hardin, Arturo Ramirez, Eric Kaldjian, Evan Y. Yu, Heather H. Cheng, Todd A. Yezefski, Andrew C. Hsieh, Petros Grivas, Bruce Montgomery, Peter S. Nelson, Michael T. Schweizer, Daniel E. Sabath, Steven Blinka   +16 more
wiley   +1 more source