Results 61 to 70 of about 1,106,628 (289)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Free Vibration Analysis Of Isotropic Rectangular Plates On Winkler Foundation Using Differential Transform Method

open access: yesInternational Journal of Applied Mechanics and Engineering, 2013
A differential transform method (DTM) is used to analyze free transverse vibrations of isotropic rectangular plates resting on a Winkler foundation. Two opposite edges of the plates are assumed to be simply supported.
Y. Kumar
doaj   +1 more source

Tilings of Rectangular Regions by Rectangular Tiles: Counts Derived from Transfer Matrices [PDF]

open access: yes, 2014
Step by step completion of a left-to-right tiling of a rectangular floor with tiles of a single shape starts from one edge of the floor, considers the possible ways of inserting a tile at the leftmost uncovered square, passes through a sequence of rugged
Mathar, Richard J.
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

PENGEMBANGAN LKS BERCIRIKAN GUIDED DISCOVERY LEARNING PADA MATERI SEGI EMPAT UNTUK SISWA KELAS VII MTS

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2016
The objective of the study is to the produce students’ worksheet using the Guided Discovery Learning it is valid, practical and effective. This is a research and developmental design which adopted the model of Plomp.
Ismatul Maula   +2 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

On L′ (2, 1)–Edge Coloring Number of Regular Grids

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
In this paper, we study multi-level distance edge labeling for infinite rectangular, hexagonal and triangular grids. We label the edges with non-negative integers.
Deepthy D., Kureethara Joseph Varghese
doaj   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth   +8 more
wiley   +1 more source

Analysis of Non-Linear Probabilistic Hybrid Systems

open access: yes, 2011
This paper shows how to compute, for probabilistic hybrid systems, the clock approximation and linear phase-portrait approximation that have been proposed for non probabilistic processes by Henzinger et al.
Assouramou, Joseph, Desharnais, Josée
core   +2 more sources

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

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