Results 301 to 310 of about 622,442 (395)

Leiomyoma of Rectum [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1929
openaire   +3 more sources

Neoadjuvant chemoradiotherapy with capecitabine and irinotecan guided by UGT1A1 status in patients with locally advanced rectal cancer: 5‐year update of the CinClare trial

open access: yesCancer Communications, EarlyView.
Abstract Background The optimal regimen and chemotherapy intensity are still under investigation for neoadjuvant treatment of locally advanced rectal cancer (LARC). The CinClare trial has demonstrated improved pathologic complete response (pCR) with the addition of irinotecan to neoadjuvant chemoradiotherapy (CRT) guided by uridine diphosphate ...
Zhen Zhang   +24 more
wiley   +1 more source

Risk of colorectal cancer by family history of both colorectal carcinomas and colorectal polyps: a nationwide cohort study

open access: yesCancer Communications, EarlyView.
Abstract Background The increased risk of colorectal cancer (CRC) associated with family history of both colorectal in situ or invasive carcinomas (Stage 0 to IV) and colorectal polyps is attributed solely to family history of CRC, resulting in an underestimation of the actual risk. We aimed to assess the association between overall and early‐onset CRC
Yuqing Hu   +6 more
wiley   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

open access: yesCancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang   +18 more
wiley   +1 more source

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker   +7 more
wiley   +1 more source

Factors Influencing Resection Time in Endoscopic Submucosal Dissection for Rectal Neuroendocrine Tumors. [PDF]

open access: yesDEN Open
Nakatani S   +12 more
europepmc   +1 more source

Combined Biologics and Exclusive Enteral Nutrition Promote Early Transmural Healing and Improve Long‐Term Outcomes in Crohn's Disease: A Multicenter Retrospective Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Study design and flow chart. From October 2016 to 2024, we searched the Crohn’s disease (CD) patient databases of three IBD centers in Hubei Province and identified 598 CD patients. Among them, 179 were in clinical remission and 38 had mild disease and were therefore excluded based on the study criteria.
Haixia Ren   +16 more
wiley   +1 more source

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