Results 311 to 320 of about 622,442 (395)

A Successful Simultaneous Robotic Resection of Giant Uterine Fibroids and Rectal Cancer. [PDF]

open access: yesJ Anus Rectum Colon
Furutani Y   +10 more
europepmc   +1 more source

Large Language Models for Clinical Trial Protocol Assessments

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The purpose was to evaluate the utility of large language models (LLMs) for reviewing the statistical analysis plan (SAP) and pharmacokinetics–pharmacodynamics (PK–PD) components of clinical trial protocols. Clinical trial protocols and SAPs were obtained from clinicaltrials.gov for a testbed of 15 small‐molecule drugs, biologics, and global antibiotic
Euibeom Shin   +2 more
wiley   +1 more source

The Empty Bladder is Preferred in Some Cases of Radiation Therapy for Rectal Cancer. [PDF]

open access: yesAdv Radiat Oncol
Ospovat I   +9 more
europepmc   +1 more source

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

open access: yesBarrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely   +14 more
wiley   +1 more source

High Source Strength of Most Blister Packs Delivered for 125I Seed Brachytherapy: A Case Report. [PDF]

open access: yesCureus
Takanashi M   +6 more
europepmc   +1 more source

Acute dyspnoea in cancer patients: Prevalence of acute heart failure, resource use and diagnostic accuracy of natriuretic peptides

open access: yesEuropean Journal of Heart Failure, EarlyView.
Cancer patients presenting to the emergency department ED with dyspnoea. Among 2153 patients presenting to the ED with dyspnea, 473 (22.0%) had an active or past cancer. Acute heart failure (AHF) was the most common final diagnosis in both groups. Pneumonia and cancer‐related dyspnoea were more common in cancer patients.
Paolo Bima   +20 more
wiley   +1 more source

Adverse Outcome Pathways Applied to Space Radiation Research

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Long‐duration spaceflight exposes astronauts to various stressors that can alter human physiology, potentially causing immediate and long‐term health effects. These stressors can damage biomolecules, cells, tissues, and organs, leading to adverse outcomes.
Vinita Chauhan   +18 more
wiley   +1 more source

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