Results 1 to 10 of about 13,935 (115)

Results From a Phase 2, Open-Label Study Evaluating the Safety, Tolerability, and Effect on Ataxia of GLM101 in Three Adult Patients With PMM2-CDG. [PDF]

J Inherit Metab Dis
ABSTRACT Phosphomannomutase 2 congenital disorder of glycosylation (PMM2‐CDG) is a rare, autosomal recessive disease caused by PMM2 deficiency, which impairs conversion of mannose‐6‐phosphate into mannose‐1‐phosphate (M1P) and disrupts N‐linked glycosylation.
Serrano M, Epifani F, Marino R, McWilliams P.   +3 more
europepmc   +2 more sources

Post mortem MRI of cholinergic white matter pathways across neurodegenerative diseases. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Cholinergic white matter pathway (CWMP) degeneration is central in Alzheimer's disease (AD) and Lewy body disease (LBD). CWMP degeneration can be assessed in vivo using magnetic resonance imaging (MRI) proxies, but neuropathological validation is limited.
López-González FJ, Nemy M, Jerele C, Jiménez-Pérez A, López-Martínez MJ, Jonkman L, Rábano A, Sánchez-Juan P, Grothe MJ, Ferreira D.   +9 more
europepmc   +2 more sources

Liver and Spleen Stiffness as Non-Invasive Tools Assessing Liver Congestion in Patients With Budd-Chiari Syndrome. [PDF]

Liver Int
ABSTRACT Background and Aims Assessing liver congestion and portal hypertension (PHT) in Budd–Chiari syndrome (BCS) remains challenging. We evaluated liver and spleen stiffness measurements (LSM, SSM) obtained by transient elastography as non‐invasive tools for identifying clinically meaningful liver congestion in BCS.
Fodor A, Thompson MA, Nicoara-Farcau O, Belmonte E, Garcia-Criado Á, Darnell A, Pérez-Campuzano V, Vizcarra P, Requejo I, Falga Á, Veléz M, Fernandez I, Sueiras A, Torres S, Gazda J, Baiges A, Shalaby S, Ojeda A, Martin DS, Procopet B, Hernández-Gea V, Turon F, García-Pagan JC.   +22 more
europepmc   +2 more sources

Performance of pyDock in 8th CAPRI: Energy-Based Scoring Applied to Docking and AlphaFold Models. [PDF]

Proteins
ABSTRACT The 8th CAPRI edition has shown a significant evolution in the field of protein–protein complex structure prediction. We have participated in all 11 targets proposed in this edition, involving domain‐domain, protein–protein, protein‐peptide, and protein‐DNA interactions, including homo‐ and hetero‐meric interfaces.
Rodríguez-Lumbreras LA, Rosell M, Romero-Durana M, Monteagudo V, Glaser F, Fernandez-Recio J.   +5 more
europepmc   +2 more sources

Effect of Biofertilizers on Broccoli Yield and Soil Quality Indicators

Horticulturae, 2023
High rates of fertilizer applications potentially have significant environmental consequences, such as soil and water contamination and biodiversity loss.
Irene Ollio, Vanesa Santás-Miguel, Diego Soto Gómez, Eva Lloret, Virginia Sánchez-Navarro, Silvia Martínez-Martínez, Catalina Egea-Gilabert, Juan A. Fernández, David Fernández Calviño, Raúl Zornoza   +9 more
doaj   +1 more source

Estudio sobre el estigma percibido y el estigma experimentado según los usuarios de servicios de salud mental en la Ciudad de Buenos Aires: Su impacto en la recuperación

Revista Iberoamericana de Psicología, 2021
Testimonios en primera persona de personas con padecimiento mental permiten observar que el estigma es una dinámica social que conforma uno de los más importantes obstáculos para la recuperación personal.
Norma Irene Geffner, Martín Agrest
doaj   +1 more source

Hacia la recuperación: Enfoques terapéuticos para potenciar el tratamiento del trastorno por uso del alcohol

Mètode Science Studies Journal: Annual Review, 2022
Actualmente, los tratamientos con mayor grado de evidencia para la dependencia del alcohol son aquellos que, sobre una base cognitivo-conductual, conforman programas multidisciplinares, que incluyen dimensiones psicológicas, sociológicas y médicas.
Rosa Jurado-Barba, Ana Sion, Laura Esteban-Rodríguez, Andrés Martínez-Maldonado, Gabriel Rubio-Valladolid   +4 more
doaj   +1 more source

El Centro de Interpretación del Centro Histórico de Lima. Alcances y proyección

Turismo y Patrimonio, 2020
Con el objetivo de conocer la situación del Centro de Interpretación del Centro Histórico de Lima, su contexto, problemas y perspectivas, se realizó una investigación en la que se entrevistó a 32 personas y se efectuó un análisis FODA basado en la ...
Natalia T. Deza de la Vega
doaj   +1 more source

Comparison of different scales for the evaluation of anxiety and compliance with anesthetic induction in children undergoing scheduled major outpatient surgery

Perioperative Medicine, 2021
Introduction Anxiety in children triggered by a scheduled surgical intervention is a major issue due to its frequency and consequences. Preoperative anxiety is associated with increased patient fear and agitation on anesthetic induction.
Alberto Vieco-García, Amanda López-Picado, Manuel Fuentes, Laura Francisco-González, Belén Joyanes, Carmen Soto, Ana Garcia de la Aldea, Carlos Gonzalez-Perrino, Esther Aleo   +8 more
doaj   +1 more source

Caffeine supplementation improves countermovement jump in youth soccer players: a pilot study

Revista Española de Nutrición Humana y Dietética, 2017
Introduction: The objective of this study was to analyze the effect of caffeine ingestion in soccer performance, particularly in the countermovement jump test (CMJ).
Juan Diego Hernández-Camacho, Javier Vázquez-Carrión, Elena Fuentes-Lorca, Heliodoro Moya-Amaya   +3 more
doaj   +1 more source