ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
II. Removal by Abdominal Section of a Large Sarcoma of the Kidney, Which had Undergone Extensive Cystic Degeneration. Recovery from the Operation. Rapid Recurrence of the Disease [PDF]
C. T. CULLINGWORTH, W. Bruce Clarke
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Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting +12 more
wiley +1 more source
JACKSONIAN EPILEPSY, CONVULSIONS BEGINNING IN THE LEFT ORBICULARIS PALPEBRARUM AND EXTENDING TO THE LEFT HAND AND ARM???APOPLECTIC CYST FOUND BENEATH THE UPPER FACE CENTRE AND DRAINED???NO RECURRENCE OF CONVULSIONS [PDF]
Howell T. Pershing
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ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun +95 more
wiley +1 more source
Ultra-Early Recurrence of Atrial Fibrillation After Direct Cardioversion Predicts Late Recurrence After Ablation for Persistent Atrial Fibrillation. [PDF]
Sugiyama H +11 more
europepmc +1 more source
Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong +7 more
wiley +1 more source
II. Recurrence phenomena in terrestrial magnetism
Charles Chree, J. M. Stagg
openalex +1 more source
GASTRO-ENTEROSTOMY FOLLOWED BY RECURRENCE OF SYMPTOMS. [PDF]
Fredk. Bowreman Jessett
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