Results 71 to 80 of about 1,879,819 (343)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Recurrence of random walk traces

, 2005
We show that the edges crossed by a random walk in a network form a recurrent graph a.s. In fact, the same is true when those edges are weighted by the number of crossings.Comment: Published at http://dx.doi.org/10.1214/009117906000000935 in the Annals
Benjamini, Itai, Gurel-Gurevich, Ori, Lyons, Russell   +2 more
core   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Endoscopic management of large laterally spreading colorectal tumors (LSTs): a comparative study of techniques and outcomes

Zaporožskij Medicinskij Žurnal
Laterally spreading colorectal tumors (LSTs) are associated with a risk of high-grade dysplasia and potential malignant transformation. Endoscopic resection is the standard of care for non-invasive LSTs, with the choice of technique guided by lesion size,
V. S. Tkachov, O. M. Kiosov, A. V. Klymenko   +2 more
doaj   +1 more source

An Unusual Presentation of Low-grade Chondrosarcoma of the First Metatarsal Bone requiring extensive Resection: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Chondrosarcoma (CS) is one of the common malignant bone tumours arising from chondrocytes with variable degrees of malignancy. It is mainly noted in flat bones like the pelvis and scapula, and sometimes in long bones like the proximal femur.
D Udayakumar, V udaya, B suresh Gandhi, Naveen Jegaprasath   +3 more
doaj   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Local recurrences for mixed germ cell tumors without scrotal violation, is metastatic disease around the corner? A case report

Future Science OA
We hereby report the case of a 40-year-old male, who initially underwent a left inguinal orchiectomy for a stage Is mixed germ cell tumor achieving an R0 status.
Georges Abi Tayeh, Constance Michel, Xavier Durand   +2 more
doaj   +1 more source

Oncological Safety and Recurrence in the Surgical Treatment of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma of the Scalp [PDF]

, 2022
Johannes Zeller, Jurij Kiefer, David Braig, Oscar Winninger, Daniel Kraus, Salome Hagelstein, Steffen U. Eisenhardt   +6 more
openalex   +1 more source

Excision margins in breast conserving surgery [PDF]

, 2015
The ideal excision margin in breast conserving surgery is still a matter of debate. The aim is to see if there is any correlation between increasing excision margin distance and local recurrence rate.
Cassar, Noel, Debono, Joseph, Torpiano, Paul   +2 more
core