Results 111 to 120 of about 105,284,140 (301)

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Discovering the Fascinating Pattern in the Geometric Representation of Non-intersecting Chords on the Circle within the Motzkin Sequence

JOIV: International Journal on Informatics Visualization
This study explores the Motzkin sequence and introduces a new sequence, the Wing sequence, derived from a novel geometric representation of directed paths.
Haslinda Ibrahim, Maizon Mohd Darus, Sharmila Karim   +2 more
doaj   +1 more source

A generalised Emerson recurrence relation

, 2008
The Emerson (1968, Biometrics 24, 695–701) recurrence relation has many important applications in statistics. However, the original derivation applied only to discrete distributions.
O. Thas (2052637), John Rayner (21131888), B. De Boeck (21285929)   +2 more
core  

Recurrence Relation and Accurate Value on Inverse Moment of Discrete Distributions [PDF]

, 2015
Properties of the generalized hypergeometric series functions are employed to get the recurrence relation for inverse moments and inverse factorial moments of some discrete distributions.
ChunYuan Wang, Wuyungaowa
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Development of a Summation Formula Connected to Hyper-Geometric Function, Contiguous Relation and Recurrence Relation

, 2012
The aim of the present paper is to develop a summation formula based on half argument connected to hypergeometric function, contiguous relation and recurrence ...
Chaudhary, M.P.
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Local Frobenius Analysis of the Sequential Conformable Heun Equation at Three Finite α-Singular Points

Science Journal of University of Zakho
In this study, a specific Frobenius framework is proposed for the sequential conformable Heun equation in the original variable. The corresponding substitution z = xα, y(x) = Y (z) determines the relevant scaled parameters and establishes precise ...
Isam Najemadeen, Erdal Bas
doaj   +1 more source