Results 111 to 120 of about 104,121,840 (292)
Binomial sums about Bernoulli, Euler and Hermite polynomials [PDF]
Discrete Mathematics Letters, 2020 Xiaoyuan Wang, Wenchang Chu
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Recurrence-free survival by NAMPT IHC score.
, 2019 Kaplan-Meier curves showing recurrence-free survival of patients with NAMPT+ (blue line) and NAMPT- (red line) PDA. Median OS: 12.0 months (NAMPT+) vs. 13.5 months (NAMPT-); P-value: 0.34.
Po Hien Ear (6444044) +8 more
core +1 more source
Generalization of Spivey's recurrence relation [PDF]
In 2008, Spivey found a recurrence relation for the Bell numbers. We consider the probabilistic r-Bell polynomials associated with which are a probabilistic extension of the r-Bell polynomials. Here Y is a random variable whose moment generating function
Kim, Taekyun, Kim, Dae San
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On the Truncated Zipf Distribution and Its Structural Properties with Applications
MathematicsThe discrete version of the Pareto distribution, popularly known as the Zipf distribution, and its truncated version are not new in the literature but several structural properties have not yet been discussed, and nor has its application to a wide range ...
Indranil Ghosh, Hannah Phirman
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source