Results 141 to 150 of about 3,946,822 (379)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Sequences of twice-iterated Δw-Gould–Hopper Appell polynomials

Journal of Taibah University for Science
In this paper, we introduce general sequence of twice-iterated [Formula: see text]-(degenerate) Gould–Hopper Appell polynomials (TI-DGHAP) via discrete [Formula: see text]-Gould–Hopper Appell convolution. We obtain some of their characteristic properties
Neslihan Biricik, Bayram Çekim, Mehmet Ali Özarslan   +2 more
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Recurrence of Products of Linear Recursive Functions [PDF]

arXiv, 2013
We study the recurrence of the product of n functions, each of which satisfies the same recurrence relation.
arxiv  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Generalized-Hypergeometric Solutions of the General Fuchsian Linear ODE Having Five Regular Singularities

Axioms, 2019
We show that a Fuchsian differential equation having five regular singular points admits solutions in terms of a single generalized hypergeometric function for infinitely many particular choices of equation parameters.
Artur Ishkhanyan, Clemente Cesarano
doaj   +1 more source

On the integral values of a curious recurrence [PDF]

arXiv, 2014
We discuss a problem initially thought for the Mathematical Olympiad but which has several interpretations. The recurrence sequences involved in this problem may be generalized to recurrence sequences related to a much larger set of diophantine equations.
arxiv  

Recurrence relations for the super-Halley method

Computers & Mathematics with Applications, 1998
In this paper we give sufficient conditions in order to assure the convergence of the super-Halley method in Banach spaces. We use a system of recurrence relations analogous to those given in the classical Newton-Kantorovich theorem, or those given for Chebyshev and Halley methods by different authors. © 1998 Elsevier Science Ltd. All rights reserved.
Gutiérrez, J.M., Hernández, M.A.
openaire   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

On a family of recurrences that includes the Fibonacci and the Narayana recurrences [PDF]

arXiv, 2017
We survey and prove properties a family of recurrences bears in relation to integer representations, compositions, the Pascal triangle, sums of digits, Nim games and Beatty sequences.
arxiv