Results 161 to 170 of about 3,946,822 (379)

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Spectral solutions for the time-fractional heat differential equation through a novel unified sequence of Chebyshev polynomials

open access: yesAIMS Mathematics
In this article, we propose two numerical schemes for solving the time-fractional heat equation (TFHE). The proposed methods are based on applying the collocation and tau spectral methods. We introduce and employ a new set of basis functions: The unified
Waleed Mohamed Abd-Elhameed   +1 more
doaj   +1 more source

Chain recurrence rates and topological entropy [PDF]

open access: yesarXiv, 2008
We investigate the properties of chain recurrent, chain transitive, and chain mixing maps (generalizations of the well-known notions of non-wandering, topologically transitive, and topologically mixing maps). We describe the structure of chain transitive maps. These notions of recurrence are defined using $\ep$-chains, and the minimal lengths of these $
arxiv  

Establishment and biological characterization of radioresistant colorectal cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu   +10 more
wiley   +1 more source

Data‐driven performance metrics for neural network learning

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri   +2 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

The Laguerre Constellation of Classical Orthogonal Polynomials

open access: yesMathematics
A linear functional u is classical if there exist polynomials ϕ and ψ with degϕ≤2 and degψ=1 such that Dϕ(x)u=ψ(x)u, where D is a certain differential, or difference, operator. The polynomials orthogonal with respect to the linear functional u are called
Roberto S. Costas-Santos
doaj   +1 more source

Relation Between Preoperative Ct Findings in Rectal Cancer and Local Recurrence Rate: A Pilot Study [PDF]

open access: bronze, 1993
Takeshi Nishioka   +5 more
openalex   +1 more source

Home - About - Disclaimer - Privacy