Results 91 to 100 of about 2,576,822 (318)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Optical Coherence Tomography Angiography Findings in Ocular Toxoplasmosis with Multiple Recurrences
Ovi Sofia,1,2 I Nyoman Surya Ari Wahyudi,3 Loeki Enggar Fitri,4 Seskoati Prayitnaningsih,2 Hani Susianti5 1Doctoral Program in Medical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; 2Department of Ophthalmology, Faculty of ...
Sofia O +4 more
doaj
The Role of Immune Cells in Recurrent Spontaneous Abortion [PDF]
Dan Li +4 more
openalex +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Purpose: To analyze the complications and their managements in Descemet′s stripping endothelial keratoplasty (DSEK) in consecutive 430 cases by single surgeon in a tertiary eye hospital.
Samar K Basak, Soham Basak
doaj +1 more source
A submanifold \(f: M^m \to \mathbb{R}^{m+d}\) is said to have pointwise \(k\)-planar normal section (P\(k\)-PNS) if, for each normal section \(\gamma\), the set \(\{\gamma'(0), \gamma''(0), {\cdots} , \gamma^{(k+1)}(0) \}\) is linearly dependent. Such an \(M\) is called proper (\(\text{PP}k\text{-PNS}\) if it is not P(\(k-1\))-PNS [\textit{B.-Y.
Arslan, Kadri +3 more
openaire +4 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Context: Children with learning disabilities might have difficulties to communicate effectively and give reliable responses as required in various visual function testing procedures.
Nurul Farhana Abu Bakar, Ai-Hong Chen
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source

