Results 261 to 270 of about 2,576,822 (318)

Early Time Courses of Recurrent Venous Thromboembolism and Bleeding during Apixaban or Dalteparin Therapy for Patients with Cancer

Alexander T. Cohen, Katherine Creeper, Raza Alikhan, Chaozer Er, Jean M. Connors, Menno V. Huisman, Andrés J. Muñoz Martín, Giorgio Vescovo, Rupert Bauersachs, Walter Ageno, Giancarlo Agnelli, Cecilia Becattini   +11 more
openalex   +2 more sources

Short-Term Traffic Prediction Under Non-Recurrent Incident Conditions Integrating Data-Driven Models and Traffic Simulation

, 2020
Sajjad Shafiei, Adriana‐Simona Mihăiţă, Hoang T. Nguyen, Charles R. Bentley, Chunwei Cai   +4 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Loss of antiphospholipid antibody positivity decreases the risk of recurrent thrombosis in thrombotic antiphospholipid syndrome. [PDF]

Rheumatology (Oxford)
Gaspar P, Cruz-Machado AR, Abrantes AM, Costa F, Parreira I, Lopes AR, Costa-Silva R, Chícharo AT, Martins JR, Marques JP, Santos D, Romão VC, Graca L, Fonseca JE.   +13 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Advances in Clinical Trials of Boron Neutron Capture Therapy. [PDF]

Research (Wash D C)
Li X, Liu Z, Liu K, Wang C, Liu Z, Xu X.
europepmc   +1 more source