Results 71 to 80 of about 3,225,031 (302)

Malignant recurrent orbital solitary fibrous tumor

open access: yesIndian Journal of Pathology and Microbiology, 2023
Solitary fibrous tumor (SFT) is a rare mesenchymal tumor of fibroblastic origin commonly occurring in pleura. It can occur at many extrapleural sites but is rare in orbit. Most cases are benign and recurrence is not unusual in the head and neck and orbit
Jaydeep N Pol   +3 more
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Repeat Resection for Recurrent Glioblastoma in the WHO 2021 Era: A Longitudinal Matched Case-Control Study

open access: yesBrain Sciences
Background and Objectives: This study aims to evaluate the overall survival benefits of repeat resection in patients with recurrent glioblastoma, IDH-wildtype (rGBM), and to identify factors for long-term survival, including the role of clinical ...
Melike Mut   +5 more
doaj   +1 more source

Recurrent Surface Homeomorphisms

open access: yes, 1998
An orientation-preserving recurrent homeomorphism of the two-sphere which is not the identity is shown to admit exactly two fixed points. A recurrent homeomorphism of a compact surface with negative Euler characteristic is periodic.Comment: 10 pages ...
Kolev, Boris, Peroueme, Marie-Christine
core   +4 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Recurrent bilateral TMJ dislocation in a 20-month-old child: A rare case presentation

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Temporomandibular joint dislocations are extremely rare in children and only four such cases have been reported in the literature so far. However, a case of recurrent bilateral mandibular dislocation is even rare to occur and a report of one such case is
S Chhabra, N Chhabra
doaj   +1 more source

Deep Recurrent Survival Analysis

open access: yes, 2018
Survival analysis is a hotspot in statistical research for modeling time-to-event information with data censorship handling, which has been widely used in many applications such as clinical research, information system and other fields with survivorship ...
Qin, Jiarui   +6 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Case Report: A novel chemotherapy-free regimen combined with photodynamic therapy, target therapy, and immunotherapy in a geriatric male with huge recurrent scalp and facial angiosarcoma: a report of an extremely rare case and literature review

open access: yesFrontiers in Immunology
Angiosarcomas are sporadic vascular neoplasms among the most aggressive subtypes of soft tissue sarcomas. In addition, vast and multiple recurrent superficial scalp and facial angiosarcomas are very complex and extremely difficult to manage.
Ewetse Paul Maswikiti   +15 more
doaj   +1 more source

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