Results 251 to 260 of about 717,209 (287)

Effects of xylazine on airway function in ponies with recurrent airway obstruction

American Journal of Veterinary Research, 1992
SUMMARY The effect of iv administration of the α2-adrenoceptor agonist xylazine hydrochloride (0.5 mg/kg of body weight) was examined in ponies with recurrent obstructive pulmonary disease, commonly called heaves. Six ponies with the disease (principals) were studied during clinical remission and during an acute attack of airway obstruction ...
R V, Broadstone, P R, Gray, N E, Robinson, F J, Derksen   +3 more
openaire   +2 more sources

Effects of furosemide on ponies with recurrent airway obstruction

Pulmonary Pharmacology, 1991
The effect of aerosol and intravenous administrations of furosemide was examined in ponies with recurrent obstructive pulmonary disease, commonly called 'heaves'. This recurrent airway disease bears many similarities to human asthma. Six ponies with the disease (principal animals) were studied during clinical remission and during an acute attack of ...
R V, Broadstone, N E, Robinson, P R, Gray, P S, Woods, F J, Derksen   +4 more
openaire   +2 more sources

Recurrent airway obstruction—heaves

Veterinary Clinics of North America: Equine Practice, 2003
Heaves, or recurrent airway obstruction (RAO), is a chronic respiratory disease featuring lower airway inflammation, bronchoconstriction, and mucus accumulation. Inhaled organic dusts and T helper 2 type immunologic reactions are involved in the complex pathophysiology of RAO. Clinical signs vary and alternate with remission periods.
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A novel model for equine recurrent airway obstruction

Veterinary Immunology and Immunopathology, 2002
Equine recurrent airway obstruction (RAO; a term combining both chronic obstructive pulmonary disease (COPD) and summer pasture associated obstructive pulmonary disease (SPAOPD)) is one of the most common equine respiratory diseases with up to 50% of horses affected worldwide.
K S, Bowles, R E, Beadle, S, Mouch, S S, Pourciau, M A, Littlefield-Chabaud, C, Le Blanc, L, Mistric, D, Fermaglich, D W, Horohov   +8 more
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Recurrent airway obstruction

Equine Health, 2016
Chris Shepherd MRCVS examines the disease, its causes and prevention
openaire   +1 more source

Coughing, mucus accumulation, airway obstruction, and airway inflammation in control horses and horses affected with recurrent airway obstruction

American Journal of Veterinary Research, 2003
Abstract Objective—To investigate relationships between cough frequency and mucus accumulation, airway obstruction, and airway inflammation and to determine effects of dexamethasone on coughing and mucus score. Animals—13 horses with recurrent airway obstruction( RAO and 6 control horses.
N Edward, Robinson, Cathy, Berney, Sue, Eberhart, Heather L, deFeijter-Rupp, Andrew M, Jefcoat, Cornelis J, Cornelisse, Vincent M, Gerber, Frederik J, Derksen   +7 more
openaire   +2 more sources

Efficacy of salmeterol xinafoate in horses with recurrent airway obstruction

Journal of the American Veterinary Medical Association, 2001
Abstract Objective—To determine the onset, magnitude, and duration of bronchodilation after administration of aerosolized salmeterol xinafoate in horses with recurrent airway obstruction. Design—Randomized controlled study Animals—6 horses with recurrent airway obstruction.
S L, Henrikson, B R, Rush
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[Genetics of recurrent airway obstruction (RAO)].

DTW. Deutsche tierarztliche Wochenschrift, 2008
Recurrent airway obstruction (RAO) is a multifactorial and polygenic disease. Affected horses are typically 7 years of age or older and show exercise intolerance, increased breathing effort, coughing, airway neutrophilia, mucus accumulation and hyperreactivity as well as cholinergic bronchospasm.
Gerber, Vinzenz, Swinburne, J E, Blott, S C, Nussbaumer, Päivi, Ramseyer, Alessandra Anna, Klukowska-Rötzler, J, Dolf, Gaudenz, Marti, Eliane Isabelle, Burger, Dominik Cyrill, Leeb, Tosso   +9 more
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In vitro responses of airway smooth muscle from horses with recurrent airway obstruction

Pulmonary Pharmacology, 1991
The in vitro contractile and relaxant responses of tracheal smooth muscle strips (TSM) and third-generation bronchi (3B) of control horses and horses with recurrent obstructive disease (heaves) were compared. Acetylcholine (ACH) sensitivity of the diseased tissues was less than that of tissues from control horses, especially at the level of the third ...
R V, Broadstone, P H, LeBlanc, F J, Derksen, N E, Robinson   +3 more
openaire   +2 more sources

Recurrent Otitis and Upper Airway Obstruction

2019
Metabolic checkpoint kinase mTOR, is activated by PI3K, and has a prominent role in promoting dynamic changes in T cell metabolism Gain-of-function mutation in PI3K gene leads to increased mTOR function, which in turn can cause ...
Narges Eslami, Mehrnaz Mesdaghi, Zahra Chavoshzadeh   +2 more
openaire   +1 more source